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ecumicin

 
National Institutes of Health

Papers overview

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2019
2019
ClpC1 is an emerging new target for the treatment of Mycobacterium tuberculosis infections, and several cyclic peptides (ecumicin… Expand
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2019
2019
Addressing the urgent need to develop novel drugs against drug-resistant Mycobacterium tuberculosis ( M. tb) strains, ecumicin… Expand
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2018
2018
Mycobacterium tuberculosis can remain dormant in the host, an ability that explains the failure of many current tuberculosis… Expand
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2018
2018
The first total synthesis of the potent anti-mycobacterial cyclic depsipeptide natural product ecumicin is described. Synthesis… Expand
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2017
2017
Ecumicin is a well-known and potent inhibitor of Mycobacterium tuberculosis. Although the target of ecumicin is caseinolytic… Expand
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2017
2017
Keywords: Oligopeptides; 1H iterative Full Spin Analysis (HiFSA); Ecumicin; Computational Iteration; Structure elucidation 
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2017
2017
This report describes an approach using 1H NMR iterative full-spin analysis (HiFSA) to extract definitive structural information… Expand
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2016
2016
Ecumicin is a novel anti-tuberculosis agent produced by Nonomuraea sp. MJM5123 as a new strain of actinomycetes. First, in order… Expand
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Highly Cited
2015
Highly Cited
2015
Drug-resistant tuberculosis (TB) has lent urgency to finding new drug leads with novel modes of action. A high-throughput… Expand
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2014
2014
The new tuberculosis (TB) lead ecumicin (1), a cyclic tridecapeptide, was isolated from Nonomuraea sp. MJM5123, following a high… Expand
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