dynemicin A

An enediyne antineoplastic antibiotic hybrid containing an anthraquinone moiety isolated from the bacterium Micromonospora chersina. The… (More)

Topic mentions per year

Topic mentions per year

1989-2017
024619892017

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2008
2008
A concept for designing nontoxic enediyne-based antitumor drugs that was previously suggested (J. Am. Chem. Soc. 2000, 122, 8245… (More)
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2007
2007
The Bergman cyclization of the natural enediyne dynemicin A in its triggered form (2) bound to the minor groove of DNA is… (More)
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2005
2005
Addition of Diaion HP-20 or Amberlite XAD-8 resin to the fermentation ofMicromonospora chersina ATCC 53710 enhanced the… (More)
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1995
1995
BACKGROUND Dynemicin A is an exceedingly potent antitumor antibiotic derived from microbial fermentation that cleaves double… (More)
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1995
1995
Dynemicin A is a potent antibacterial and antitumor antibiotic having a striking hybrid structure of both anthraquinone as a DNA… (More)
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1992
1992
Supplementing the culture ofMicromonospora chersina sp. nov. No. M956-1 with NaI (0.5 mg/l) enhanced the production of dynemicin… (More)
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1991
1991
The reaction products of methyl thioglycolate with dynemicin A, dynemicin H and dynemicin S, were isolated by HPLC purification… (More)
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1991
1991
New antibiotics, dynemicins O (3), P (4) and Q (5), were isolated from the culture broth of Micromonospora chersina M956-1, the… (More)
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1991
1991
Dynemicin A, a novel antibiotic containing the bicyclo[7.3.1]-1,5-diyn-3-ene and 1,4,6-trihydroxyanthraquinone functionalities… (More)
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1990
1990
Dynemicin A, which is a hybrid antitumor antibiotic containing anthraquinone and enediyne cores, effectively breaks DNA strands… (More)
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