duloxetine

Known as: N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine, N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide 
A drug used to treat depression and peripheral neuropathy (pain, numbness, tingling, burning, or weakness in the hands or feet) that can occur with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
IMPORTANCE There are no known effective treatments for painful chemotherapy-induced peripheral neuropathy. OBJECTIVE To… (More)
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Highly Cited
2012
Highly Cited
2012
This study aims to individualize the selection of drugs for neuropathic pain by examining the potential coupling of a given drug… (More)
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Highly Cited
2008
Highly Cited
2005
Highly Cited
2005
The aim of this study was to examine the efficacy and safety of duloxetine, a balanced and potent dual reuptake inhibitor of… (More)
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Highly Cited
2005
Highly Cited
2005
This was a 12-week, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of duloxetine, a… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Assess efficacy and safety of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor, on the reduction… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To assess the efficacy and safety of duloxetine, a serotonin and norepinephrine reuptake inhibitor, in subjects with… (More)
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Highly Cited
2004
Highly Cited
2004
5-Hydroxytryptamine (serotonin) (5-HT) and norepinephrine (NE) are implicated in modulating descending inhibitory pain pathways… (More)
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Highly Cited
2003
Highly Cited
2003
Duloxetine is a potent and balanced dual inhibitor of serotonin and norepinephrine reuptake being investigated for the treatment… (More)
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Highly Cited
2001
Highly Cited
2001
The blockade of serotonin (5-HT) and norepinephrine (NE) transporters in vitro and in vivo by the dual 5-HT/NE reuptake… (More)
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