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dopamine-beta-monooxygenase activity

Known as: dopamine-B-hydroxylase activity, 3,4-dihydroxyphenethylamine beta-oxidase activity, dopamine beta-hydroxylase activity 
Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O. [EC:1.14.17.1, RHEA:19120]
National Institutes of Health

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Dopamine-beta-monooxygenase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Molecular basis for polysialylation: A novel polybasic polysialyltransferase domain (PSTD) of 32 amino acids unique to the α2,8-polysialyltransferases is essential for polysialylation
To determine the molecular basis of eukaryotic polysialylation, the function of a structurally unique polybasic motif of 32 amino… Expand
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2003
2003
Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2).
Ascorbic acid (vitamin C) is a cofactor required in catecholamine synthesis for conversion of dopamine to norepinephrine by… Expand
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Highly Cited
2001
Highly Cited
2001
A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus.
Dopamine-beta-hydroxylase (D beta H) catalyzes the conversion of dopamine to norepinephrine and is released from sympathetic… Expand
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1999
1999
Catecholamine storage vesicle protein expression in genetic hypertension.
Chromogranin A expression is heritable in humans, and both plasma chromogranin A concentration and its releasable adrenal and… Expand
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1999
1999
Decreased dopamine beta-hydroxylase activity in unipolar geriatric delusional depression
BACKGROUND Decreased dopamine beta-hydroxylase (DBH) activity has been reported in unipolar psychotic depression. DBH comparisons… Expand
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1992
1992
Evidence for an altered dopamine beta-hydroxylase activity in migraine and tension-type headache.
Sympathetic dysfunction is often present in migraine. It has been suggested that serum dopamine-beta-hydroxylase (D beta H) can… Expand
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1986
1986
Ascorbic acid specifically enhances dopamine beta-monooxygenase activity in resting and stimulated chromaffin cells.
  • Michael Levine
  • The Journal of biological chemistry
  • 1986
    • Corpus ID: 24163908
Ascorbic acid enhancement of norepinephrine formation from tyrosine in cultured bovine chromaffin cells was characterized in… Expand
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1982
1982
Opioid peptides and noradrenaline co-exist in large dense-cored vesicles from sympathetic nerve
The possibility that opioid peptides and noradrenaline co-exist not only in the desheathed bundle of bovine splenic nerve which… Expand
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1977
1977
Plasma noradrenaline concentrations in experimental renovascular hypertension in the rat.
1. Plasma noradrenaline concentrations and dopamine beta-hydroxylase activity have been measured at various stages in the… Expand
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1976
1976
Vascular and brain dopamine beta-hydroxylase activity in young spontaneously hypertensive rats.
Dopamine beta-hydroxylase activity was higher in mesenteric vessels, adrenal glands, and serum of 3-week-old spontaneously… Expand
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