FAQ

dopamine-beta-monooxygenase activity

Known as: dopamine-B-hydroxylase activity, 3,4-dihydroxyphenethylamine beta-oxidase activity, dopamine beta-hydroxylase activity 
Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O. [EC:1.14.17.1, RHEA:19120]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
0246819682017

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Related topics

1 relation
Dopamine-beta-monooxygenase

Related mentions per year

Related mentions per year

1968-2017
1960198020002020
dopamine-beta-monooxygenase activity
Dopamine-beta-monooxygenase

Papers overview

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2003
2003
The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity.
There is currently a great deal of interest in using linkage disequilibrium (LD) mapping to locate both disease and quantitative… (More)
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2003
2003
Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2).
Ascorbic acid (vitamin C) is a cofactor required in catecholamine synthesis for conversion of dopamine to norepinephrine by… (More)
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2002
2002
Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression.
BACKGROUND Plasma activity of dopamine beta-hydroxylase (DbetaH), the enzyme that converts dopamine to norepinephrine, is… (More)
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Highly Cited
2001
Highly Cited
2001
A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus.
Dopamine-beta-hydroxylase (D beta H) catalyzes the conversion of dopamine to norepinephrine and is released from sympathetic… (More)
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1999
1999
Catecholamine storage vesicle protein expression in genetic hypertension.
Chromogranin A expression is heritable in humans, and both plasma chromogranin A concentration and its releasable adrenal and… (More)
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1999
1999
Decreased dopamine beta-hydroxylase activity in unipolar geriatric delusional depression.
BACKGROUND Decreased dopamine beta-hydroxylase (DBH) activity has been reported in unipolar psychotic depression. DBH comparisons… (More)
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1988
1988
Ascorbic acid and Mg-ATP co-regulate dopamine beta-monooxygenase activity in intact chromaffin granules.
Ascorbic acid and Mg-ATP were found to regulate norepinephrine biosynthesis in intact secretory vesicles synergistically and… (More)
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1987
1987
Purified cytochrome b561 catalyzes transmembrane electron transfer for dopamine beta-hydroxylase and peptidyl glycine alpha-amidating monooxygenase activities in reconstituted systems.
Cytochrome b561 from bovine adrenal medulla chromaffin granules has been purified by fast protein liquid chromatography… (More)
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1986
1986
Ascorbic acid specifically enhances dopamine beta-monooxygenase activity in resting and stimulated chromaffin cells.
Ascorbic acid enhancement of norepinephrine formation from tyrosine in cultured bovine chromaffin cells was characterized in… (More)
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1982
1982
Opioid peptides and noradrenaline co-exist in large dense-cored vesicles from sympathetic nerve.
The possibility that opioid peptides and noradrenaline co-exist not only in the desheathed bundle of bovine splenic nerve which… (More)
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