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dopamine-beta-monooxygenase activity

Known as: dopamine-B-hydroxylase activity, 3,4-dihydroxyphenethylamine beta-oxidase activity, dopamine beta-hydroxylase activity 
Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O. [EC:1.14.17.1, RHEA:19120]
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The imidazo[1,5-a]pyridine skeleton provides a versatile platform for the generation of new types of stable N-heterocyclic… Expand
Highly Cited
2001
Highly Cited
2001
Dopamine-beta-hydroxylase (D beta H) catalyzes the conversion of dopamine to norepinephrine and is released from sympathetic… Expand
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Highly Cited
1989
Highly Cited
1989
Two markers for noradrenergic neurons: 1) desmethylimipramine sensitive norepinephrine (NE) uptake and 2) dopamine beta… Expand
1986
1986
  • M. Levine
  • The Journal of biological chemistry
  • 1986
  • Corpus ID: 24163908
Ascorbic acid enhancement of norepinephrine formation from tyrosine in cultured bovine chromaffin cells was characterized in… Expand
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Highly Cited
1986
Highly Cited
1986
The role(s) of ascorbic acid in dopamine beta-hydroxylation was studied in primary cultures of bovine adrenomedullary chromaffin… Expand
Highly Cited
1982
Highly Cited
1982
The possibility that opioid peptides and noradrenaline co-exist not only in the desheathed bundle of bovine splenic nerve which… Expand
Highly Cited
1981
Highly Cited
1981
This report describes the application of 500-MHz 1H-NMR spectroscopy for the determination of the primary structures of the… Expand
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Highly Cited
1977
Highly Cited
1977
1. Plasma noradrenaline concentrations and dopamine beta-hydroxylase activity have been measured at various stages in the… Expand
Highly Cited
1976
Highly Cited
1976
Dopamine beta-hydroxylase activity was higher in mesenteric vessels, adrenal glands, and serum of 3-week-old spontaneously… Expand
Highly Cited
1972
Highly Cited
1972
1. Soluble lysates and membranes were prepared from chromaffin granules isolated from bovine adrenal medulla. The detergent N… Expand