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Clinical trials have shown the benefits of cholinesterase inhibitors for the treatment of mild-to-moderate Alzheimer's… Expand BACKGROUND
Alzheimer's disease is the most common cause of dementia in older people. One of the aims of therapy is to inhibit the… Expand BACKGROUND
Mild cognitive impairment is a transitional state between the cognitive changes of normal aging and early Alzheimer's… Expand CONTEXT
Memantine is a low- to moderate-affinity, uncompetitive N-methyl-D-aspartate receptor antagonist. Controlled trials have… Expand BACKGROUND
Cholinesterase inhibitors produce small improvements in cognitive and global assessments in Alzheimer's disease. We… Expand To the Editor:
In their recently published, 1-year prospective, double blind, placebo-controlled study, Winblad et al.1 examined… Expand Objective: To investigate the efficacy and safety of donepezil in patients with moderate to severe AD (standardized Mini-Mental… Expand Objective: To examine the effects of donepezil compared with placebo on the preservation of function in patients with AD over a 1… Expand Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately… Expand The efficacy and safety of donepezil as a treatment for patients with mild to moderate Alzheimer's disease (AD) was investigated… Expand