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donepezil

Known as: DONEP, Donepezilum, donepezil [Chemical/Ingredient] 
The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (6)

5-desmethyl donepezilAriceptE 2020Eranz
Alzheimer's DiseaseDonepezil hydrochlorideDonepezil hydrochloride 10 MG Oral TabletDonepezil hydrochloride 5 MG Disintegrating Oral Tablet [Aricept]

Broader (4)

Cholinesterase InhibitorsIndansNootropic Agentspiperidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Cognition as a target in major depression: New developments
2012
2012
Efficacy and Safety of Donepezil 23 mg versus Donepezil 10 mg for Moderate-to-Severe Alzheimer’s Disease: A Subgroup Analysis in Patients Already Taking or Not Taking Concomitant Memantine
Background/Aims: A large multicenter trial of donepezil 23 mg/day versus donepezil 10 mg/day for moderate-to-severe Alzheimer’s… 
Review
2011
Review
2011
The cholinergic system, sigma-1 receptors and cognition
Highly Cited
2011
Highly Cited
2011
5-HT4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment
Highly Cited
2009
Highly Cited
2009
Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
Highly Cited
2007
Highly Cited
2007
Characterization of reversible and pseudo-irreversible acetylcholinesterase inhibitors by means of an immobilized enzyme reactor.
Review
2006
Review
2006
Do cholinergic therapies have disease-modifying effects in Alzheimer’s disease?
Highly Cited
2005
Highly Cited
2005
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors*
The neuroprotective properties of bis(7)-tacrine, a novel dimeric acetylcholinesterase (AChE) inhibitor, on glutamate-induced… 
Review
2002
Review
2002
CLINICAL AND COST-EFFECTIVENESS OF DONEPEZIL, RIVASTIGMINE, AND GALANTAMINE FOR ALZHEIMER'S DISEASE
Objectives: Systematic review of the clinical and cost-effectiveness of donepezil, rivastigmine, and galantamine for people… 
Review
2001
Review
2001
Muscarinic agonists and antagonists in the treatment of Alzheimer's disease.
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