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donepezil

Known as: DONEP, Donepezilum, donepezil [Chemical/Ingredient] 
The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Dementia is a clinical syndrome in which an acquired cognitive deficit interferes with a person's independence in daily… Expand
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Review
2017
Review
2017
BACKGROUND The clinical benefit of memantine for Alzheimer's disease (AD) remains inconclusive. OBJECTIVE We performed an… Expand
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Review
2016
Review
2016
OBJECTIVE To summarise existing systematic reviews that assess the effects of non-pharmacological, pharmacological and… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Clinical trials have shown the benefits of cholinesterase inhibitors for the treatment of mild-to-moderate Alzheimer's… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Mild cognitive impairment is a transitional state between the cognitive changes of normal aging and early Alzheimer's… Expand
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Highly Cited
2004
Highly Cited
2004
CONTEXT Memantine is a low- to moderate-affinity, uncompetitive N-methyl-D-aspartate receptor antagonist. Controlled trials have… Expand
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To evaluate the long-term clinical efficacy and safety of donepezil versus placebo over 1 year in patients with mild to… Expand
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To investigate the efficacy and safety of donepezil in patients with moderate to severe AD (standardized Mini-Mental… Expand
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Highly Cited
1999
Highly Cited
1999
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately… Expand
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Highly Cited
1998
Highly Cited
1998
The efficacy and safety of donepezil as a treatment for patients with mild to moderate Alzheimer's disease (AD) was investigated… Expand
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