Donepezil hydrochloride

Known as: 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride, donepezil hcl 
The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
05101519982018

Papers overview

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Highly Cited
2012
Highly Cited
2012
OBJECTIVE Because cholinergic deficits are prominent in dementia with Lewy bodies (DLB), we investigated the effects of a… (More)
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2011
2011
OBJECTIVES To determine whether donepezil hydrochloride can reduce the prevalence and severity of delirium in older adults… (More)
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2008
2008
Donepezil hydrochloride is a potent and selective acetylcholinesterase inhibitor and has been treated for Alzheimer's disease, in… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To study the safety and efficacy of a cholinesterase inhibitor, donepezil hydrochloride, for the treatment of dementia… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The only approved pharmacological approach for the symptomatic treatment of Alzheimer's disease in Japan is the use of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Donepezil hydrochloride is a selective acetylcholinesterase inhibitor approved for the symptomatic treatment of mild… (More)
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Highly Cited
2001
Highly Cited
2001
UNLABELLED The aim of this SPECT study was to investigate the effects of donepezil on regional cerebral blood flow (rCBF) in… (More)
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2000
2000
This study evaluated efficacy and safety of donepezil hydrochloride (donepezil) at 5 mg/day in patients with mild to moderately… (More)
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1999
1999
The effects of oral administration of the centrally acting acetylcholinesterase (AChE) inhibitors, donepezil hydrochloride… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Donepezil hydrochloride (Aricept) is a selective acetylcholinesterase inhibitor developed for the treatment of… (More)
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