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Donepezil hydrochloride

Known as: 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine Hydrochloride, donepezil hcl 
The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Objective: Because cholinergic deficits are prominent in dementia with Lewy bodies (DLB), we investigated the effects of a… Expand
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Highly Cited
2012
Highly Cited
2012
Parkinson's disease dementia (PDD) is associated with cholinergic deficits. This report presents an efficacy and safety study of… Expand
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Highly Cited
2011
Highly Cited
2011
The aim of this study was to develop a taste-masked oral disintegrating film (ODF) containing donepezil, with fast disintegration… Expand
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Highly Cited
2010
Highly Cited
2010
Electrostatic spinning (Electrospinning, ES) was applied to prepare Donepezil HCl loaded nanofibers as a poten- tial orally… Expand
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Review
2007
Review
2007
  • Ben Seltzer
  • Expert opinion on pharmacotherapy
  • 2007
  • Corpus ID: 23291154
Donepezil hydrochloride is the most widely prescribed drug for Alzheimer’s disease (AD). The main mechanism of action through… Expand
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Highly Cited
2005
Highly Cited
2005
Objective: To study the safety and efficacy of a cholinesterase inhibitor, donepezil hydrochloride, for the treatment of dementia… Expand
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Review
2002
Review
2002
A wide range of evidence shows that cholinesterase (ChE) inhibitors can interfere with the progression of Alzheimer's disease (AD… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Donepezil hydrochloride is a selective acetylcholinesterase inhibitor approved for the symptomatic treatment of mild… Expand
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Review
2000
Review
2000
A wide range of evidence shows that acetylcholinesterase (AChE) inhibitors can interfere with the progression of Alzheimer's… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Donepezil hydrochloride (Aricept) is a selective acetylcholinesterase inhibitor developed for the treatment of… Expand
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