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Donepezil hydrochloride

Known as: 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine Hydrochloride, donepezil hcl 
The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby… 
National Institutes of Health

Related topics

Related topics

9 relations
Alzheimer's DiseaseCytochrome P450 2D6, humanDonepezil hydrochloride 10 MG Oral TabletDonepezil hydrochloride 5 MG Disintegrating Oral Tablet [Aricept]

Narrower (2)

AriceptNamzaric

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Neuroprotection against vascular dementia after acupuncture combined with donepezil hydrochloride: P300 event related potential
Acupuncture can be used to treat various nervous system diseases. Here, 168 vascular dementia patients were orally administered… 
2011
2011
Bionanotechnologies for treatment and diagnosis of Alzheimer's disease.
  • S. Moein Moghimi
  • Nanomedicine : nanotechnology, biology, and…
  • 2011
  • Corpus ID: 41847681
Review
2008
Review
2008
Key lessons learned from short-term treatment trials of cholinesterase inhibitors for amnestic MCI
ABSTRACT Objective: This paper reviews the key lessons learned from the first published short-term, placebo-controlled trial of a… 
2006
2006
Acetylcholinesterase inhibitor acting on the brain improves detrusor overactivity caused by cerebral infarction in rats
2004
2004
Concurrent administration of donepezil HCl and levodopa/carbidopa in patients with Parkinson's disease: assessment of pharmacokinetic changes and safety following multiple oral doses.
AIM The use of acetylcholinesterase inhibitors for the treatment of comorbid Alzheimer's disease in Parkinson's disease (PD… 
2003
2003
Acetylcholinesterase Inhibitor (Donepezil Hydrochloride) Reduces Heart Rate Variability
Summary: An acetylcholinesterase inhibitor (donepezil hydrochloride) has recently been used for the treatment of senile dementia… 
2003
2003
Beneficial Effect of Donepezil on Sensorimotor Function After Stroke
Berthier ML, Pujol J, Gironell A, Kulisevsky J, Deus J, Hinojosa J, Soriano-Mas C: Beneficial effect of donepezil on sensorimotor… 
Highly Cited
2002
Highly Cited
2002
Concurrent administration of donepezil HCl and ketoconazole: assessment of pharmacokinetic changes following single and multiple doses.
AIM The aim of this study was to examine the pharmacokinetics of donepezil HCl and ketoconazole separately, and in combination… 
1998
1998
Concurrent administration of donepezil HCl and theophylline: assessment of pharmacokinetic changes following multiple-dose administration in healthy volunteers.
AIM The aim of the study was to evaluate the pharmacokinetics of theophylline administered alone, and in combination with… 
1998
1998
Concurrent administration of donepezil HCl and digoxin: assessment of pharmacokinetic changes.
AIM The aim of this study was to examine the pharmacokinetics of donepezil HCl and digoxin separately, and in combination… 
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