Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

disoxaril

Known as: 5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methylisoxazole 
A compound with activity against human picornaviruses. Disoxaril binds to the hydrophobic pocket within the viral VP1 capsid protein and prevents… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
In this work we evaluated the ability of 2,6-di-O-methyl-beta-cyclodextrin (DM-beta-Cyd) to include the anti-rhinovirus drug… Expand
Is this relevant?
2000
2000
Effects of enviroxime and disoxaril, inhibitors of replication of some picornaviruses with known mechanisms of action, alone or… Expand
Is this relevant?
1999
1999
When combined, enviroxime and disoxaril, two selective picornavirus inhibitors, exert a marked synergistic inhibitory effect on… Expand
Is this relevant?
1995
1995
The effects of enviroxime, disoxaril and ribavirin in pair combinations on poliovirus type 1 (Mahoney) replication in FL cells… Expand
Is this relevant?
1994
1994
A series of 1,2,4-oxadiazoles has been prepared as ester bioisosteres and tested against 15 human rhinovirus serotypes, and the… Expand
Is this relevant?
1993
1993
A series of tetrazole analogues of Win 54954, a broad-spectrum antipicornavirus compound, has been synthesized to address the… Expand
Is this relevant?
1992
1992
A series of conformationally restricted analogs of disoxaril has been synthesized and evaluated against human rhinovirus types… Expand
Is this relevant?
1991
1991
14 S subunits of poliovirus at 37 degrees undergo a rapid thermodenaturation, whereby all neutralizing epitopes are lost. This… Expand
Is this relevant?
1990
1990
Disoxaril (5-[7-[4(4,5-dihydro-2-oxazolyl)phenoxy]-heptyl]-3- methylisoxazole) protects poliovirus procapsids against alkaline… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1987
1987
Disoxaril [WIN 51711, 5-[7-[4(4,5-dihydro-2-oxazolyl)phenoxy]heptyl]-3- methylisoxazole] inhibits the replication of polioviruses… Expand
Is this relevant?