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diphenylmethoxyacetic acid

Known as: (diphenylmethoxy)acetate, (diphenylmethoxy)acetic acid, DPMA acid 
 
National Institutes of Health

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2 relations

Broader (2)

AcetatesBenzhydryl Compounds

Papers overview

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Review
2006
Review
2006
Poisonings with diphenhydramine--a survey of 68 clinical and 55 death cases.
The antihistaminic drug diphenhydramine (DPH) is mainly used as a sedative, hypnotic and antiemetic. In many countries it is over… Expand
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2004
2004
Identification of diphenhydramine metabolites in human urine by capillary electrophoresis-ion trap-mass spectrometry.
The identification of diphenhydramine (DH) metabolites that are frequently observed in the capillary zone electrophoresis (CZE… Expand
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2004
2004
Comparative Pharmacokinetics of Diphenhydramine in Camels and Horses after Intravenous Administration
The pharmacokinetics of diphenhydramine (DPHM) was compared in camels (n = 8) and horses (n = 6) following intravenous (i.v… Expand
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2000
2000
Pharmacokinetics and renal excretion of diphenhydramine and its metabolites, diphenylmethoxyacetic acid and diphenhydramine-N-oxide, in developing lambs.
The developmental disposition of diphenhydramine (DPHM) and its metabolites, diphenylmethoxyacetic acid (DPMA) and DPHM-N-oxide… Expand
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1999
1999
Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep.
Deamination to diphenylmethoxyacetic acid (DPMA) is the major route of diphenhydramine (DPHM) clearance in many species. In this… Expand
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1999
1999
Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep.
We investigated the contribution of the liver and gut to systemic diphenhydramine (DPHM) clearance in adult nonpregnant sheep in… Expand
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1998
1998
Drug disposition in the maternal-fetal unit : studies with diphenhydramine and valproic acid in pregnant sheep
Diphenhydramine (DPHM, a high clearance amine) and valproic acid (VPA, a low clearance carboxylic acid) disposition was examined… Expand
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1997
1997
Estimation of transplacental and nonplacental diphenhydramine clearances in the fetal lamb: the impact of fetal first-pass hepatic drug uptake.
Previous estimates of maternal and fetal placental and nonplacental clearances in pregnant sheep using a two-compartment open… Expand
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1995
1995
Simultaneous analysis of diphenylmethoxyacetic acid, a metabolite of diphenhydramine, and its deuterium-labeled stable isotope analog in ovine plasma and urine.
Diphenylmethoxyacetic acid (DPMA) is a major metabolite of diphenhydramine in monkeys, dogs, and humans. The metabolic fate of… Expand
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1970
1970
Species Differences in the Metabolism of Diphenhydramine (Benadryl 1 ) 2
Summary Tritium-labeled diphenhydramine given iv to rhesus monkeys produced a rapid drop in plasma levels of unchanged drug, but… Expand
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