dihydronicotinamide riboside quinone reductase activity

Known as: NQO2, NAD(P)H:quinone oxidoreductase 2 activity, 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity 
Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone. [EC… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2015
012319902015

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Quinone reductase 2 (NQO2) is an FAD-linked enzyme and the only known human target of two antimalarial drugs, primaquine (PQ) and… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
2011
2011
Short-chain quinones are described as potent antioxidants and in the case of idebenone have already been under clinical… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2010
2010
The purpose of the work was to identify novel inhibitors of the enzyme NQO2. Using computational molecular modelling, a QSAR (R(2… (More)
Is this relevant?
2009
2009
Imatinib represents the first in a class of drugs targeted against chronic myelogenous leukemia to enter the clinic, showing… (More)
  • table 1
  • figure 4
  • figure 1
Is this relevant?
2009
2009
The physiological function of NAD(P)H:quinone oxidoreductase (NQO1, DT-diaphorase) is to detoxify potentially reactive quinones… (More)
Is this relevant?
2006
2006
NRH:quinone oxidoreductase 2 (NQO2) is a cytosolic flavoprotein that utilizes NRH as electron donor. The present studies… (More)
Is this relevant?
2005
2005
CB1954 is an attractive prodrug for directed-enzyme prodrug therapy (DEPT) and a conventional prodrug against tumors in which the… (More)
Is this relevant?
2000
2000
A novel prodrug activation system, endogenous in human tumor cells, is described. A latent enzyme-prodrug system is switched on… (More)
Is this relevant?
1997
1997
Human NAD(P)H:quinone acceptor oxidoreductase-2 (NQO2) has been prepared using an Escherichia coli expression method. NQO2 is… (More)
Is this relevant?
1990
1990
NAD(P)H:quinone oxidoreductases (NQOs) are flavoproteins that catalyze the oxidation of NADH or NADPH by various quinones and… (More)
Is this relevant?