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dihydronicotinamide riboside quinone reductase activity
Known as:
NQO2
, NAD(P)H:quinone oxidoreductase 2 activity
, 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity
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Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone. [EC…
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National Institutes of Health
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Related topics
Related topics
3 relations
NQO2 gene
Ribosyldihydronicotinamide Dehydrogenase [Quinone]
Narrower (1)
NRH:quinone oxidoreductase 2 activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2*
K. Leung
,
B. Shilton
Journal of Biological Chemistry
2013
Corpus ID: 2002531
Background: The flavoenzyme quinone reductase 2 (NQO2) has an unknown cellular function and binds many drugs and bioactive…
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2013
2013
NAD(P)H: Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 Polymorphisms in Papillary Thyroid Microcarcinoma: Correlation with Phenotype
Junguee Lee
,
K. S. Kim
,
+8 authors
Y. Jo
Yonsei medical journal
2013
Corpus ID: 17317744
Purpose NAD(P)H:Quinone Oxidoreductase 1 (NQO1) C609T missense variant (NQO1*2) and 29 basepair (bp)-insertion/deletion (I29/D…
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2012
2012
Ah receptor- and Nrf2-gene battery members: modulators of quinone-mediated oxidative and endoplasmic reticulum stress.
K. Bock
Biochemical Pharmacology
2012
Corpus ID: 5155613
2009
2009
Antiproliferative effects of resveratrol and the mediating role of resveratrol targeting protein NQO2 in androgen receptor-positive, hormone-non-responsive CWR22Rv1 cells.
T. Hsieh
Anticancer Research
2009
Corpus ID: 26044576
Trans-resveratrol, a polyphenol present in red wines and various human foods, was first reported to exhibit chemopreventive…
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2009
2009
5‐MCA‐NAT does not act through NQO2 to reduce intraocular pressure in New‐Zealand white rabbit
P. Alarma‐Estrany
,
A. Crooke
,
J. Pintor
Journal of Pineal Research
2009
Corpus ID: 30089497
Abstract: Solid data support the idea that the MT3 melatonin binding site is an enzyme, quinone reductase 2 (NQO2), rather than…
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2008
2008
Dissecting the Role of Multiple Reductases in Bioactivation and Cytotoxicity of the Antitumor Agent 2,5-Diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1)
Chao Yan
,
J. Kepa
,
D. Siegel
,
I. Stratford
,
D. Ross
Molecular Pharmacology
2008
Corpus ID: 9226793
2,5-Diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1) is a novel antitumor diaziridinyl benzoquinone derivative…
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Review
2006
Review
2006
[Clozapine-induced agranulocytosis: genetic risk factors and an immunologic explanatory model].
Y. Güzelcan
,
W. Scholte
Tijdschrift voor psychiatrie
2006
Corpus ID: 11064605
BACKGROUND Clozapine, an atypical antipsychotic used in the treatment of refractory schizophrenia, causes agranulocytosis in 0.8…
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Highly Cited
2000
Highly Cited
2000
Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy.
R. Knox
,
T. C. Jenkins
,
S. Hobbs
,
S. Chen
,
R. Melton
,
P. Burke
Cancer Research
2000
Corpus ID: 25195736
A novel prodrug activation system, endogenous in human tumor cells, is described. A latent enzyme-prodrug system is switched on…
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Review
2000
Review
2000
Structure-function studies of DT-diaphorase (NQO1) and NRH: quinone oxidoreductase (NQO2).
Shiuan Chen
,
Kebin Wu
,
Richard J. Knox
Free Radical Biology & Medicine
2000
Corpus ID: 41251829
2000
2000
Mouse NRH:quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression.
D. J. Long
,
A. Jaiswal
Gene
2000
Corpus ID: 32390637
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