FAQ

Ribosyldihydronicotinamide Dehydrogenase [Quinone]

Known as: Ribosyldihydronicotinamide Dehydrogenase, NRH Dehydrogenase [Quinone] 2, NQO2 
Ribosyldihydronicotinamide dehydrogenase [quinone] (231 aa, ~26 kDa) is encoded by the human NQO2 gene. This protein is involved in the metabolism of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
024619922016

Related topics

Related topics

7 relations
CytoplasmEnzyme GeneNQO2 geneOxidation-Reduction
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ribosyldihydronicotinamide Dehydrogenase [Quinone]
Cytoplasm
Oxidation-Reduction
Enzyme Gene
dihydronicotinamide riboside quinone reductase activity
Quinone Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Role of NQO1 609C>T and NQO2-3423G>A polymorphisms in susceptibility to gastric cancer in Kashmir valley.
NADPH: quinone oxidoreductase 1 (NQO1) and dihydronicotinamide riboside: quinone oxidoreductase 2 (NQO2) are cytosolic enzymes… (More)
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2010
2010
Pleiotropic mechanisms facilitated by resveratrol and its metabolites.
Resveratrol has demonstrated cancer chemopreventive activity in animal models and some clinical trials are underway. In addition… (More)
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2009
2009
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
Imatinib represents the first in a class of drugs targeted against chronic myelogenous leukemia to enter the clinic, showing… (More)
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2008
2008
An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets.
Recently protein kinases have emerged as some of the most promising drug targets; and therefore, pharmaceutical strategies have… (More)
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2002
2002
Discovery of novel targets of quinoline drugs in the human purine binding proteome.
The quinolines have been used in the treatment of malaria, arthritis, and lupus for many years, yet the precise mechanism of… (More)
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2002
2002
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.
Dihydronicotinamide riboside (NRH):quinone oxidoreductase 2 (NQO2) is a flavoenzyme that catalyzes the reductive metabolism of… (More)
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2002
2002
Differential gene expression of NAD(P)H:quinone oxidoreductase and NRH:quinone oxidoreductase in human hepatocellular and biliary tissue.
NAD(P)H:quinone oxidoreductase (NQO1) and dihydronicotinamide riboside:quinone oxidoreductases (NQO2) are cytosolic flavoproteins… (More)
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2001
2001
An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2.
Individual vulnerability to reactive intermediates and oxidative stress accompanying metabolism of endogenous toxic compounds in… (More)
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1999
1999
Crystal structure of human quinone reductase type 2, a metalloflavoprotein.
In mammals, two separate but homologous cytosolic quinone reductases have been identified: NAD(P)H:quinone oxidoreductase type 1… (More)
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1997
1997
Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
Human NAD(P)H:quinone acceptor oxidoreductase-2 (NQO2) has been prepared using an Escherichia coli expression method. NQO2 is… (More)
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