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Ribosyldihydronicotinamide Dehydrogenase [Quinone]

Known as: Ribosyldihydronicotinamide Dehydrogenase, NRH Dehydrogenase [Quinone] 2, NQO2 
Ribosyldihydronicotinamide dehydrogenase [quinone] (231 aa, ~26 kDa) is encoded by the human NQO2 gene. This protein is involved in the metabolism of… Expand
National Institutes of Health

Related topics

Related topics

7 relations
CytoplasmEnzyme GeneNQO2 geneOxidation-Reduction
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pleiotropic mechanisms facilitated by resveratrol and its metabolites.
Resveratrol has demonstrated cancer chemopreventive activity in animal models and some clinical trials are underway. In addition… Expand
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Review
2009
Review
2009
Melatonin: signaling mechanisms of a pleiotropic agent.
Melatonin acts both as a hormone of the pineal gland and as a local regulator molecule in various tissues. Quantities of total… Expand
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Review
2008
Review
2008
Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?
Melatonin is a neurohormone that has been claimed to be involved in a wide range of physiological functions. Nevertheless, for… Expand
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2008
2008
An Unbiased Evaluation of CK2 Inhibitors by Chemoproteomics
Recently protein kinases have emerged as some of the most promising drug targets; and therefore, pharmaceutical strategies have… Expand
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Review
2005
Review
2005
Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance.
Melatonin has been shown to protect against oxidative stress in various, highly divergent experimental systems. There are many… Expand
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Review
2005
Review
2005
NRH:quinone reductase 2: an enzyme of surprises and mysteries.
Quinone reductase 2 has been discovered in 1961 and rediscovered in 1997. Because of its sequence homology with quinone reductase… Expand
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Highly Cited
2004
Highly Cited
2004
Crystal structure of quinone reductase 2 in complex with resveratrol.
Resveratrol has been shown to have chemopreventive, cardioprotective, and antiaging properties. Here, we report that resveratrol… Expand
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Review
2003
Review
2003
Circadian Rhythms, Oxidative Stress, and Antioxidative Defense Mechanisms
Endogenous circadian and exogenously driven daily rhythms of antioxidative enzyme activities and of low molecular weight… Expand
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Highly Cited
2002
Highly Cited
2002
Discovery of novel targets of quinoline drugs in the human purine binding proteome.
The quinolines have been used in the treatment of malaria, arthritis, and lupus for many years, yet the precise mechanism of… Expand
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Highly Cited
2000
Highly Cited
2000
Identification of the Melatonin-binding SiteMT 3 as the Quinone Reductase 2*
The regulation of the circadian rhythm is relayed from the central nervous system to the periphery by melatonin, a hormone… Expand
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