dihydroisoquinoline

 

Topic mentions per year

Topic mentions per year

1975-2017
02419752017

Papers overview

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2016
2016
Obesity is a serious health problem that increases the risk of many complications, including diabetes and cardiovascular disease… (More)
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2013
2013
The structure-activity relationship of a series of dihydroisoquinoline BACE-1 inhibitors is described. Application of structure… (More)
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2012
2012
N,N'-(4,4'-Sulfonylbis(4,1-phenylene))bis(2-cyanoacetamid) 2 was utilized as a key intermediate for the synthesis of novel… (More)
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2012
2012
A high-throughput screen identified 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acid as a novel, highly potent (low nM… (More)
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2008
2008
Optically active tetrahydroisoquinoline alkaloids, (R)-(+)-higenamine (1R) and (S)-(-)-higenamine (1 S), and their optically… (More)
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2002
2002
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) protein that reduce cAMP… (More)
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2002
2002
Brain-targeted delivery of various drugs can be successfully achieved by chemical delivery systems (CDS) that contain a 1,4… (More)
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1987
1987
We report that 6,7-dihydroxy-3,4-dihydroisoquinolines related to dopamine are potent inhibitors of catechol-O-methyltransferase… (More)
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1979
1979
The distribution of fluorescence in the rat brain after i.p. or intracerebral (i.c.) injections of a fluorescent… (More)
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1977
1977
The uptake and the accumulation of dopamine-derived fluorescent dihydroisoquinoline were demonstrated with direct fluorescence… (More)
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