developmental programmed cell death

Apoptosis, an evolutionarily conserved programme of cellular self-destruction, is essential for the development and survival of… Expand

BackgroundThe human NECDIN gene is involved in a neurodevelopmental disorder, Prader-Willi syndrome (PWS). Previously we reported… Expand

Mechanisms of plant developmental programmed cell death (PCD) have been inten- sively studied in recent years. PCD is important… Expand

Apoptosis is typically a morphologically identifiable form of programmed cell death in mammals that is regulated by genes with… Expand

Apoptotic cell death often requires caspases. Caspases are part of a family of related molecules including also paracaspases and… Expand

Bcl‐2 family proteins are key regulators of apoptosis. Both pro‐apoptotic and anti‐apoptotic members of this family are found in… Expand

The cytosolic protein APAF1, human homolog of C. elegans CED-4, participates in the CASPASE 9 (CASP9)-dependent activation of… Expand

BCL-2 family members and caspases are essential components of the death machinery in neurons. Identification of Apaf-1 as the… Expand

We reported previously that striatal excitotoxic lesion with quinolinic acid of rat pups during the first 2 weeks of postnatal… Expand

DNA fragmentation was evaluated in three instances of programmed cell death, interdigital cell death in embryonic mouse limbs… Expand