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detoxication

 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
  • Yi Jin, T. Penning
  • Annual review of pharmacology and toxicology
  • 2007
  • Corpus ID: 11863237
Aldo-keto reductases (AKRs) are soluble NAD(P)(H) oxidoreductases that primarily reduce aldehydes and ketones to primary and… Expand
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Highly Cited
2004
Highly Cited
2004
The cytochrome P450 (CYP1A1) enzyme metabolically activates many polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP… Expand
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Review
2001
Review
2001
  • F. Guengerich
  • Chemical research in toxicology
  • 2001
  • Corpus ID: 32038435
Cytochrome P450 (P450) enzymes catalyze a variety of reactions and convert chemicals to potentially reactive products as well as… Expand
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Review
1999
Review
1999
  • J. Fahey, P. Talalay
  • Food and chemical toxicology : an international…
  • 1999
  • Corpus ID: 16517275
The widespread belief that oxidative damage plays a major role in cancer, ageing, and in a number of chronic diseases has focused… Expand
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Highly Cited
1992
Highly Cited
1992
Consumption of vegetables, especially crucifers, reduces the risk of developing cancer. Although the mechanisms of this… Expand
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Review
1991
Review
1991
  • W. Levine
  • Drug metabolism reviews
  • 1991
  • Corpus ID: 23544312
Azo dyes are consumed and otherwise utilized in varying quantities in many parts of the world. Such widely used chemicals are of… Expand
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Review
1990
Review
1990
 
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Review
1984
Review
1984
  • L. Terriere
  • Annual review of entomology
  • 1984
  • Corpus ID: 42880250
Most of the known enzyme systems involved in the degradation of insecticides, other xenobiotics, and hormones of insects, appear… Expand
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Review
1983
Review
1983
Glutathione (GSH) is a strong nucleophile which reacts well with soft electrophiles, but poorly with both weak and strong… Expand
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Highly Cited
1979
Highly Cited
1979
Publisher Summary This chapter discusses the role of glutathione (GSH) and glutathione s-transferases in metabolism of chemical… Expand
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