detoxication

 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Aldo-keto reductases (AKRs) are soluble NAD(P)(H) oxidoreductases that primarily reduce aldehydes and ketones to primary and… (More)
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Highly Cited
2004
Highly Cited
2004
The cytochrome P450 (CYP1A1) enzyme metabolically activates many polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP… (More)
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Highly Cited
2003
Highly Cited
2003
Enzyme inducers such as 3H-1,2-dithiole-3-thione (D3T) enhance the detoxication of environmental carcinogens and protect against… (More)
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Highly Cited
2002
Highly Cited
2002
Gastric infection with Helicobacter pylori is a cosmopolitan problem, and is especially common in developing regions where there… (More)
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Review
2001
Review
2001
Cytochrome P450 (P450) enzymes catalyze a variety of reactions and convert chemicals to potentially reactive products as well as… (More)
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Review
1999
Review
1999
The widespread belief that oxidative damage plays a major role in cancer, ageing, and in a number of chronic diseases has focused… (More)
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Highly Cited
1992
Highly Cited
1992
Consumption of vegetables, especially crucifers, reduces the risk of developing cancer. Although the mechanisms of this… (More)
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Review
1991
Review
1991
Azo dyes are consumed and otherwise utilized in varying quantities in many parts of the world. Such widely used chemicals are of… (More)
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Review
1984
Review
1984
Most of the known enzyme systems involved in the degradation of insecticides, other xenobiotics, and hormones of insects, appear… (More)
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Review
1983
Review
1983
Glutathione (GSH) is a strong nucleophile which reacts well with soft electrophiles, but poorly with both weak and strong… (More)
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