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desmoglein 1

Known as: Desmoglein 1 [Chemical/Ingredient], Dsg1 Antigen, Desmosomal Glycoprotein 1 
A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS FOLIACEUS.
National Institutes of Health

Related topics

Related topics

11 relations
DSG1 geneDesmoglein 1 & Desmoglein 3 Ab panel:ACnc:Pt:Ser:QnDesmoglein 1 Ab:ACnc:Pt:Ser:QnIn Blood

Papers overview

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Highly Cited
2013
Highly Cited
2013
Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting
The relative contribution of immunological dysregulation and impaired epithelial barrier function to allergic diseases is still a… 
Highly Cited
2005
Highly Cited
2005
Pemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteraction.
Autoantibodies against the epidermal desmosomal cadherins desmoglein 1 (Dsg1) and Dsg3 have been shown to cause severe to lethal… 
Highly Cited
2002
Highly Cited
2002
Staphylococcal exfoliative toxin B specifically cleaves desmoglein 1.
Staphylococcal scalded skin syndrome and its localized form, bullous impetigo, show superficial epidermal blister formation… 
Highly Cited
2001
Highly Cited
2001
Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development
During melanoma development, transformed cells evade keratinocyte-mediated control by downregulating cell adhesion molecules… 
Highly Cited
2000
Highly Cited
2000
Protection against pemphigus foliaceus by desmoglein 3 in neonates.
Pemphigus foliaceus is an autoantibody-mediated blistering disease in which antibodies against desmoglein 1 cause loss of… 
Highly Cited
2000
Highly Cited
2000
The Prevalence of Antibodies against Desmoglein 1 in Endemic Pemphigus Foliaceus in Brazil
Background Pemphigus foliaceus is an autoimmune skin disease mediated by autoantibodies against desmoglein 1. The endemic form is… 
Highly Cited
1998
Highly Cited
1998
Lack of mucosal involvement in pemphigus foliaceus may be due to low expression of desmoglein 1.
Oral mucosal lesions are seen in most cases of pemphigus vulgaris, whereas they are only rarely seen in pemphigus foliaceus… 
Highly Cited
1996
Highly Cited
1996
Pemphigus vulgaris antigen (desmoglein 3) is localized in the lower epidermis, the site of blister formation in patients.
In Patients with pemphigus vulgaris, autoantibodies against the desmosomal glycoprotein desmoglein 3 (Dsg3) cause blisters due to… 
Highly Cited
1988
Highly Cited
1988
Identification of pemphigus vulgaris antigen extracted from normal human epidermis and comparison with pemphigus foliaceus antigen.
Immunoprecipitations of cultured keratinocyte extracts have shown that pemphigus vulgaris (PV) sera bind a polypeptide of 210,000… 
Highly Cited
1987
Highly Cited
1987
Human autoantibodies against a desmosomal protein complex with a calcium-sensitive epitope are characteristic of pemphigus foliaceus patients
Pemphigus foliaceus (PF) patients have antibodies against a tightly, but noncovalently bound complex of polypeptides, which… 
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