• Publications
  • Influence
The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators.
OBJECTIVE We aimed to develop consensus-based recommendations for streamlining medical communication among various health care professionals, to improve accuracy of diagnosis and treatment, and toExpand
  • 614
  • 46
Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins.
Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune skin diseases caused by autoantibodies against desmoglein (Dsg) 3 and Dsg1, respectively. Routine immunofluorescence testing ofExpand
  • 452
  • 15
Incidence of autoimmune subepidermal blistering dermatoses in a region of central Germany.
With great interest, we read the recent article by Bernard et al1in the January 1995 issue of theArchiveson the incidence and distribution of subepidermal autoimmune bullous skin diseases in threeExpand
  • 200
  • 10
Pathologic Evidence of Degeneration as a Primary Cause of Rotator Cuff Tear
Histopathologic, histochemical, and morphometric studies were done on 80 medial stumps of torn rotator cuff tendons to clarify the cause of tears. A high prevalence and diffuse distribution ofExpand
  • 299
  • 9
BP180 ELISA using bacterial recombinant NC16a protein as a diagnostic and monitoring tool for bullous pemphigoid.
Bullous pemphigoid (BP) is an acquired autoimmune subepidermal blistering disease against hemidesmosomal cytoplasmic BP230 and transmembrane BP180 proteins. Epitope mapping studies have shown thatExpand
  • 192
  • 8
Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation.
The autosomal recessive disorder lipoid proteinosis results from mutations in extracellular matrix protein 1 (ECM1), a glycoprotein expressed in several tissues (including skin) and composed of twoExpand
  • 118
  • 8
The new pemphigus variants.
Pemphigus describes a group of autoimmune diseases characterized by blisters and erosions of the skin and mucous membranes, acantholysis by histology, and autoantibodies directed against epidermalExpand
  • 223
  • 7
  • PDF
Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase.
Putrescine N-methyltransferase (PMT) is the first alkaloid-specific enzyme for nicotine and tropane alkaloid formation. The pmt gene from Nicotiana tabacum was fused to the CaMV 35S promoter andExpand
  • 61
  • 7
Antigen-specific immunoadsorption of pathogenic autoantibodies in pemphigus foliaceus.
Patients with the autoimmune blistering disease pemphigus foliaceus (PF) have circulating autoantibodies directed against the desmosomal cadherin desmoglein 1 (Dsg1). Based on the fact that purifiedExpand
  • 239
  • 6
A randomized double-blind trial of intravenous immunoglobulin for pemphigus.
BACKGROUND Pemphigus is a rare life-threatening intractable autoimmune blistering disease caused by IgG autoantibodies to desmogleins. It has been difficult to conduct a double-blind clinical studyExpand
  • 177
  • 6