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- Publications
- Influence
Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion
- M. Amagai, V. Klaus-Kovtun, J. Stanley
- Biology, Medicine
- Cell
- 29 November 1991
Pemphigus vulgaris (PV) is a life-threatening skin disease in which autoantibodies against a keratinocyte cell surface 130 kd glycoprotein, PV antigen (PVA), cause loss of cell-cell adhesion, with… Expand
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome.
- J. Stanley, M. Amagai
- Medicine
- The New England journal of medicine
- 26 October 2006
This review discusses the autoantibodies in pemphigus vulgaris and pemphigus foliaceus and the clinical and pathological similarities among these forms of pemphigus, bullous impetigo, and the… Expand
Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins.
- K. Ishii, M. Amagai, +5 authors T. Nishikawa
- Biology, Medicine
- Journal of immunology
- 15 August 1997
Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune skin diseases caused by autoantibodies against desmoglein (Dsg) 3 and Dsg1, respectively. Routine immunofluorescence testing of… Expand
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin
- Aimin Tang, M. Amagai, L. G. Granger, J. Stanley, Mark C. Uddy
- Biology, Medicine
- Nature
- 7 January 1993
LANGERHANS cells (LC) are the principal accessory cells present in epidermis1. Because LC have limited capacity for self-renewal2, epidermis is continually repopulated by as-yet uncharacterized bone… Expand
Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways.
- Y. Sasaki, E. Asamizu, +11 authors S. Tabata
- Biology, Medicine
- DNA research : an international journal for rapid…
- 2001
Jasmonates mediate various physiological events in plant cells such as defense responses, flowering, and senescence through intracellular and intercellular signaling pathways, and the expression of a… Expand
Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris.
- M. Mahoney, Z. Wang, K. Rothenberger, P. J. Koch, M. Amagai, J. Stanley
- Medicine
- The Journal of clinical investigation
- 15 February 1999
Patients with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or skin. PF and PV… Expand
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1
- M. Amagai, N. Matsuyoshi, Z. H. Wang, C. Andl, J. Stanley
- Biology, Medicine
- Nature Medicine
- 7 December 2000
Exfoliative toxin A, produced by Staphylococcus aureus, causes blisters in bullous impetigo and its more generalized form, staphylococcal scalded-skin syndrome. The toxin shows exquisite specificity… Expand
The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile.
- M. Amagai, K. Tsunoda, D. Zillikens, T. Nagai, T. Nishikawa
- Medicine
- Journal of the American Academy of Dermatology
- 1 February 1999
BACKGROUND
Some patients with pemphigus vulgaris (PV) have mucous membrane erosions with minimal skin involvement (mucosal dominant type), and others show extensive skin blisters and erosions in… Expand
External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers
- A. Kubo, K. Nagao, M. Yokouchi, H. Sasaki, M. Amagai
- Biology, Medicine
- The Journal of experimental medicine
- 21 December 2009
Outermost barriers are critical for terrestrial animals to avoid desiccation and to protect their bodies from foreign insults. Mammalian skin consists of two sets of barriers: stratum corneum (SC)… Expand
Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis.
- T. Kobayashi, M. Glatz, +6 authors K. Nagao
- Biology, Medicine
- Immunity
- 21 April 2015
Staphylococcus aureus skin colonization is universal in atopic dermatitis and common in cancer patients treated with epidermal growth factor receptor inhibitors. However, the causal relationship of… Expand
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