desflurane

Known as: 1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane, (+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether, Desfluranum 
A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Volatile anesthetics facilitate surgical procedures and imaging studies in millions of children every year. Neuronal… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND In animal models, neonatal exposure to volatile anesthetics induces neuroapoptosis, leading to memory deficits in… (More)
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Highly Cited
2011
Highly Cited
2011
General anaesthetics have enjoyed long and widespread use but their molecular mechanism of action remains poorly understood… (More)
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Review
2010
Review
2010
BACKGROUND Emergence agitation (EA) in children is increased after sevoflurane anaesthesia. The efficacy of prophylactic… (More)
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Highly Cited
2001
Highly Cited
2001
UNLABELLED We evaluated the circulating and lung oxidative status during general anesthesia established with propofol… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The authors hypothesized that the electroencephalogram (EEG) during higher anesthetic concentrations would show more… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Rapid development of acute opioid tolerance is well established in animals and is more likely to occur with large… (More)
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Highly Cited
2000
Highly Cited
2000
UNLABELLED We compared the recovery characteristics of remifentanil, desflurane, and sevoflurane when used for anesthesia in… (More)
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Highly Cited
1998
Highly Cited
1998
It is known that volatile anaesthetics protect myocardial tissue against ischaemic and reperfusion injury in vitro. In this… (More)
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1991
1991
The electroencephalographic (EEG) effects of a new inhaled anesthetic are of interest because of the potential of such agents to… (More)
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