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Isoflurane
Known as:
1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether
, 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
, Isoflurane [Chemical/Ingredient]
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A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, inhaled…
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National Institutes of Health
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Related topics
Related topics
33 relations
Broader (3)
Anesthetics
Anesthetics, Inhalation
haloether
Narrower (6)
Attane
Forane
Forene
Isoflo
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Cerebral Arterial Vasoconstriction [PE]
Depressive disorder
Drug Allergy
Enflurane
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Isoflurane-induced Neuroapoptosis in the Neonatal Rhesus Macaque Brain
A. Brambrink
,
A. Evers
,
+6 authors
J. Olney
Anesthesiology
2010
Corpus ID: 12748539
Background:Brief isoflurane anesthesia induces neuroapoptosis in the developing rodent brain, but susceptibility of non-human…
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Highly Cited
2009
Highly Cited
2009
Dexmedetomidine Attenuates Isoflurane-induced Neurocognitive Impairment in Neonatal Rats
R. Sanders
,
Jing Xu
,
+7 authors
M. Maze
Anesthesiology
2009
Corpus ID: 32692750
Background:Neuroapoptosis is induced by the administration of anesthetic agents to the young. As α2 adrenoceptor signaling plays…
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Highly Cited
2009
Highly Cited
2009
Isoflurane Differentially Affects Neurogenesis and Long-term Neurocognitive Function in 60-day-old and 7-day-old Rats
G. Stratmann
,
J. Sall
,
+8 authors
Ran Dai
Anesthesiology
2009
Corpus ID: 11945991
Background:Anesthetic agents cause cell death in the developing rodent brain and long-term, mostly hippocampal-dependent…
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Review
2004
Review
2004
Comparison of Recovery Profile After Ambulatory Anesthesia with Propofol, Isoflurane, Sevoflurane and Desflurane: A Systematic Review
Anil Gupta
,
T. Stierer
,
R. Zuckerman
,
N. Sakima
,
S. Parker
,
L. Fleisher
Anesthesia and Analgesia
2004
Corpus ID: 30352622
In this systematic review we focused on postoperative recovery and complications using four different anesthetic techniques. The…
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Highly Cited
2003
Highly Cited
2003
Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits
V. Jevtovic-Todorovic
,
R. Hartman
,
+5 authors
D. Wozniak
Journal of Neuroscience
2003
Corpus ID: 9055365
Recently it was demonstrated that exposure of the developing brain during the period of synaptogenesis to drugs that block NMDA…
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Highly Cited
2000
Highly Cited
2000
Effects of Gaseous Anesthetics Nitrous Oxide and Xenon on Ligand-gated Ion Channels: Comparison with Isoflurane and Ethanol
T. Yamakura
,
R. Harris
Anesthesiology
2000
Corpus ID: 4684919
BackgroundLigand-gated ion channels are considered to be potential general anesthetic targets. Although most general anesthetics…
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Highly Cited
1999
Highly Cited
1999
Direct cerebral vasodilatory effects of sevoflurane and isoflurane.
B. Matta
,
K. Heath
,
K. E. Tipping
,
A. Summors
Anesthesiology
1999
Corpus ID: 24927577
BACKGROUND The effect of volatile anesthetics on cerebral blood flow depends on the balance between the indirect vasoconstrictive…
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Highly Cited
1997
Highly Cited
1997
Bispectral Analysis Measures Sedation and Memory Effects of Propofol, Midazolam, Isoflurane, and Alfentanil in Healthy Volunteers
P. Glass
,
M. Bloom
,
L. Kearse
,
C. Rosow
,
P. Sebel
,
P. Manberg
Anesthesiology
1997
Corpus ID: 25962984
Background: The bispectral index (BIS), a value derived from the electroencephalograph (EEG), has been proposed as a measure of…
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Highly Cited
1996
Highly Cited
1996
Reduction of Isoflurane Minimal Alveolar Concentration by Remifentanil
E. Iáng
,
A. Kapila
,
D. Shlugman
,
J. Hoke
,
P. Sebel
,
P. Glass
Anesthesiology
1996
Corpus ID: 21776004
Background Remifentanil is a new micro‐specific opioid receptor agonist currently under investigation. The interaction between…
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Highly Cited
1995
Highly Cited
1995
Dynamic and Static Cerebral Autoregulation during Isoflurane, Desflurane, and Propofol Anesthesia
S. Strebel
,
A. Lam
,
Basil Matta
,
T. S. Mayberg
,
R. Aaslid
,
D. Newell
Anesthesiology
1995
Corpus ID: 1486214
Background Although inhalation anesthetic agents are thought to impair cerebral autoregulation more than intravenous agents…
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