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Isoflurane

Known as: 1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether, 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, Isoflurane [Chemical/Ingredient] 
A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, inhaled… 
National Institutes of Health

Related topics

Related topics

33 relations

Broader (3)

AnestheticsAnesthetics, Inhalationhaloether

Narrower (6)

AttaneForaneForeneIsoflo
Cerebral Arterial Vasoconstriction [PE]Depressive disorderDrug AllergyEnflurane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Isoflurane induces cognitive deficits in the Morris water maze task in rats
Background Postoperative cognitive dysfunction has been reported in young, middle-aged and elderly patients with greater… 
Highly Cited
2007
Highly Cited
2007
Isoflurane Preconditioning Improves Long-term Neurologic Outcome after Hypoxic–Ischemic Brain Injury in Neonatal Rats
Background:Preconditioning the brain with relatively safe drugs seems to be a viable option to reduce ischemic brain injury. The… 
Highly Cited
2007
Highly Cited
2007
Heme Oxygenase-1 Induction by the Clinically Used Anesthetic Isoflurane Protects Rat Livers From Ischemia/Reperfusion Injury
Objective:It was the aim of this study to characterize the influence of isoflurane-induced heme oxygenase-1 (HO-1) expression on… 
Highly Cited
2007
Highly Cited
2007
Improved spatial localization of post-stimulus BOLD undershoot relative to positive BOLD
Highly Cited
2002
Highly Cited
2002
Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats
Highly Cited
1999
Highly Cited
1999
Isoflurane Delays but Does Not Prevent Cerebral Infarction in Rats Subjected to Focal Ischemia
Background Several investigations have shown that volatile anesthetics can reduce ischemic cerebral injury. In these studies… 
Highly Cited
1992
Highly Cited
1992
Halothane, enflurane, and isoflurane attenuate both receptor- and non-receptor-mediated EDRF production in rat thoracic aorta.
EDRF (endothelium-derived relaxing factor) is a cellular and intercellular messenger that activates soluble guanylate cyclase. In… 
Highly Cited
1986
Highly Cited
1986
Differential Depression of Myocardial Contractility by Halothane and Isoflurane In Vitro
Depressant effects of halothane and isoflurane on isolated right ventricular guinea pig papillary muscle bathed in Tyrode's… 
Highly Cited
1984
Highly Cited
1984
Liver Circulation and Function during Isoflurane and Halothane Anesthesia
Hepatic arterial blood flow (HABF) and portal blood flow (PBF) were measured in 18 dogs while awake and during isoflurane and… 
Highly Cited
1983
Highly Cited
1983
Cardiovascular Effects of Isoflurane‐Induced Hypotension for Cerebral Aneurysm Surgery
Deliberate hypotension was induced with isoflurane in 13 patients undergoing craniotomy for clipping of aneurysms. Cardiovascular… 
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