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depudecin

Known as: Oxiranemethanol, alpha-ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)-, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-, (2R,3S,4S,5E,7S,8S,9R)-2,9- Dihydroxy-3,4;7,8-diepoxy-undeca-5,10-diene, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-alpha-Ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)oxiranemethanol 
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src oncogenes to the… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

AlkadienesEpoxy CompoundsFatty Alcohols

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Metabolite diversity in the plant pathogen Alternaria brassicicola: factors affecting production of brassicicolin A, depudecin, phomapyrone A and other metabolites
A systematic investigation of the metabolites of Alternaria brassicicola produced under various culture conditions is reported… 
Highly Cited
2009
Highly Cited
2009
Biosynthesis and role in virulence of the histone deacetylase inhibitor depudecin from Alternaria brassicicola.
Depudecin, an eleven-carbon linear polyketide made by the pathogenic fungus Alternaria brassicicola, is an inhibitor of histone… 
Highly Cited
2005
Highly Cited
2005
Diversity of type I polyketide synthase genes in the wood-decay fungus Xylaria sp. BCC 1067.
Review
2001
Review
2001
Inhibitors of histone deacetylase as new anticancer agents.
Inhibitors of histone deacetylase (HDAC) are an emerging class of anticancer agents. They induce hyperacetylation in chromatin… 
2000
2000
Biosynthesis of Depudecin, a Metabolite of Nimbya scirpicola
Feeding experiments of labeled acetates to Nimbya scirpicola proved the carbon origin of the straight-chain polyketide, depudecin… 
Highly Cited
1998
Highly Cited
1998
Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase.
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src… 
Review
1998
Review
1998
Depudecin makes a debut.
Although first identified as the product of sour grapes (acetum, vinegar), acetate recently has proven to be a sweet harvest for… 
1997
1997
Carbonylation of Alkynyl Epoxides: Synthesis of 5-Hydroxy-2,3-dienoate Esters and 2,3-Dihydrofuran-3-ol Derivatives.
The carbonylation of alkynyl oxiranes catalyzed by (MePh(2))(4)Pd in the presence of 20 atm of carbon monoxide in methanol gives… 
1995
1995
Depudecin, a microbial metabolite containing two epoxide groups, exhibits anti-angiogenic activity in vivo.
Depudecin, a microbial metabolite containing two epoxide groups, was tested for its anti-angiogenic activity in an in vivo assay… 
Highly Cited
1992
Highly Cited
1992
Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola.
A novel compound depudecin inducing the flat phenotype of ras- and src- transformed NIH3T3 cells at a concentration of 1… 
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