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depudecin

Known as: Oxiranemethanol, alpha-ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)-, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-, (2R,3S,4S,5E,7S,8S,9R)-2,9- Dihydroxy-3,4;7,8-diepoxy-undeca-5,10-diene, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-alpha-Ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)oxiranemethanol 
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src oncogenes to the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Depudecin, an eleven-carbon linear polyketide made by the pathogenic fungus Alternaria brassicicola, is an inhibitor of histone… Expand
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Highly Cited
2008
Highly Cited
2008
Regulation of gene expression is known to contribute to the long-term adaptations taking place in response to drugs of abuse… Expand
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Review
2005
Review
2005
  • Claude Monneret
  • European journal of medicinal chemistry
  • 2005
  • Corpus ID: 6312765
Histones are small basic proteins that, by complexing wtih DNA, form the nucleosome core. Repetitive units of this nucleosome led… Expand
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2005
2005
Fungal type I polyketide (PK) compounds are highly valuable for medical treatment and extremely diverse in structure, partly… Expand
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2003
2003
Neospora caninum is an apicomplexan parasite associated with abortion in cattle worldwide. Apicidin, histone deacetylase (HDAC… Expand
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Review
2001
Review
2001
  • Manfred Jung
  • Current medicinal chemistry
  • 2001
  • Corpus ID: 21484156
Inhibitors of histone deacetylase (HDAC) are an emerging class of anticancer agents. They induce hyperacetylation in chromatin… Expand
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Highly Cited
1998
Highly Cited
1998
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src… Expand
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1995
1995
Depudecin, a microbial metabolite containing two epoxide groups, was tested for its anti-angiogenic activity in an in vivo assay… Expand
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1992
1992
A novel compound depudecin inducing the flat phenotype of ras- and src- transformed NIH3T3 cells at a concentration of 1… Expand
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1992
1992
A novel compound, depudecin, induced production of the flat phenotype of Ki-ras-transformed NIH3T3 cells at the low concentration… Expand
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