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depudecin

Known as: Oxiranemethanol, alpha-ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)-, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-, (2R,3S,4S,5E,7S,8S,9R)-2,9- Dihydroxy-3,4;7,8-diepoxy-undeca-5,10-diene, (2S-(2R*(E(2R*(S*),3R*)),3R*(S*)))-alpha-Ethenyl-3-(2-(3-(1-hydroxyethyl)oxiranyl)ethenyl)oxiranemethanol 
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src oncogenes to the… 
National Institutes of Health

Papers overview

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2015
2015
The total synthesis of the natural product depudecin, an antiangiogenic microbial polyketide with inhibitory activity against… 
Highly Cited
2009
Highly Cited
2009
Depudecin, an eleven-carbon linear polyketide made by the pathogenic fungus Alternaria brassicicola, is an inhibitor of histone… 
Highly Cited
2008
Highly Cited
2008
Regulation of gene expression is known to contribute to the long-term adaptations taking place in response to drugs of abuse… 
Highly Cited
2005
Review
2001
Review
2001
  • M. Jung
  • Current medicinal chemistry
  • 2001
  • Corpus ID: 21484156
Inhibitors of histone deacetylase (HDAC) are an emerging class of anticancer agents. They induce hyperacetylation in chromatin… 
Highly Cited
1998
Highly Cited
1998
Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src… 
Review
1998
Review
1998
  • M. Privalsky
  • Proceedings of the National Academy of Sciences…
  • 1998
  • Corpus ID: 43329997
Although first identified as the product of sour grapes (acetum, vinegar), acetate recently has proven to be a sweet harvest for… 
1997
1997
The carbonylation of alkynyl oxiranes catalyzed by (MePh(2))(4)Pd in the presence of 20 atm of carbon monoxide in methanol gives… 
1995
1995
Depudecin, a microbial metabolite containing two epoxide groups, was tested for its anti-angiogenic activity in an in vivo assay… 
1992
1992
A novel compound depudecin inducing the flat phenotype of ras- and src- transformed NIH3T3 cells at a concentration of 1…