Epoxy Compounds

Known as: Epoxy Compounds [Chemical/Ingredient], Oxiranes, Epoxides 
Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
020040019452017

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50 relations

Narrower (46)

1,2-dichloro-3,4-epoxybutane1,2-epoxy-5-hexene1,3-diphenylpropene oxide2,2-bis(4-glycidyloxyphenyl)propane
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Epoxy Compounds
chemical synthesis
propylene oxide
triptolide
2,2-bis(4-glycidyloxyphenyl)propane
4-hydroxybenzoic acid diglycidyl ether

Papers overview

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Highly Cited
2009
Highly Cited
2009
The largest prospective warfarin-treated cohort supports genetic forecasting.
Genetic variants of cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) are known to influence warfarin dose… (More)
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Highly Cited
2005
Highly Cited
2005
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose.
BACKGROUND The management of warfarin therapy is complicated by a wide variation among patients in drug response. Variants in the… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
Coumarin derivatives such as warfarin represent the therapy of choice for the long-term treatment and prevention of… (More)
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Highly Cited
2004
Highly Cited
2004
Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.
Proteins secreted by activated platelets can adhere to the vessel wall and promote the development of atherosclerosis and… (More)
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Highly Cited
2003
Highly Cited
2003
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.
Docosahexaenoic acid (DHA, C22:6) is highly enriched in brain, synapses, and retina and is a major omega-3 fatty acid… (More)
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Highly Cited
1997
Highly Cited
1997
Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.
Induction of phase 2 detoxication enzymes [e.g., glutathione transferases, epoxide hydrolase, NAD(P)H: quinone reductase, and… (More)
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Highly Cited
1996
Highly Cited
1996
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.
Cigarette smoke carcinogens such as benzo[a]pyrene are implicated in the development of lung cancer. The distribution of benzo[a… (More)
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Highly Cited
1994
Highly Cited
1994
Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.
Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more… (More)
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Highly Cited
1983
Highly Cited
1983
Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation.
Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins… (More)
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Highly Cited
1980
Highly Cited
1980
Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.
2(3)-tert-Butyl-4-hydroxyanisole (BHA) is one of several widely used antioxidant food additives that protect against chemical… (More)
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