deoxypyridinoline

Known as: D-PYR, N-(5-Amino-5-Carboxypentyl)-3-Hydroxy-4-(2-Amino-2-Carboxyethyl)-5-(3-Amino-3-Carboxypropyl)Pyridine, Pyridinium, 4-(2-amino-2-carboxyethyl)-1-(5-amino-5-carboxypentyl)-3-(3-amino-3-carboxypropyl)-5-hydroxy-, hydroxide, inner salt, stereoisomer 
A pyridinium-derived moiety that forms crosslinks in type I collagen in bone. Urine levels of deoxypyridinoline are used as a correlative marker for… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The fluoropyrimidines are the mainstay chemotherapeutic agents for the treatment of many types of cancers. Detoxifying metabolism… (More)
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Highly Cited
2012
Highly Cited
2012
To evaluate evidence for de novo etiologies in schizophrenia, we sequenced at high coverage the exomes of families recruited from… (More)
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Highly Cited
2011
Highly Cited
2008
Highly Cited
2008
Structural variation (copy number variation [CNV] including deletion and duplication, translocation, inversion) of chromosomes… (More)
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Review
2004
Review
2004
The identification of genetic factors associated with either responsiveness or resistance to 5-fluorouracil (5-FU) chemotherapy… (More)
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Highly Cited
2002
Highly Cited
2002
The hypothesis of this study is that the mechanical integrity of the collagen network in bone deteriorates with age, and such… (More)
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Highly Cited
2000
Highly Cited
2000
We tested the hypothesis that the albumin-docking protein gp60, which is localized in caveolae, couples to the heterotrimeric GTP… (More)
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Highly Cited
1998
Highly Cited
1998
A biomechanical failure of the collagen network is postulated in many hypotheses of the development of osteoarthritis with… (More)
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Highly Cited
1996
Highly Cited
1996
Increased bone turnover has been suggested as a potential risk factor for osteoporotic fractures. We investigated this hypothesis… (More)
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Highly Cited
1994
Highly Cited
1994
Several studies in recent years have shown that the pyridinium crosslinks of collagen provide good urinary markers of collagen… (More)
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