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denopamine

Known as: (3,4-dimethoxyphenethylaminomethyl)-4-hydroxybenzyl alcohol, 1-(p-hydroxyphenyl)-2-((3,4-dimethoxyphenethyl)amino)ethanol, Benzenemethanol, alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-hydroxy-, (R)- 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Adrenergic beta-AgonistsCardiotonic AgentsEthanolamines

Narrower (1)

TA 064

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
The selectivity of β‐adrenoceptor agonists at human β1‐, β2‐ and β3‐adrenoceptors
  • J. Baker
  • British journal of pharmacology
  • 2010
    • Corpus ID: 31706324
Background and purpose:  There are two important properties of receptor–ligand interactions: affinity (the ability of the ligand… Expand
Highly Cited
2007
Highly Cited
2007
Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation.
BACKGROUND Some patients with Brugada syndrome experience an electrical storm of ventricular fibrillation (VF). OBJECTIVE The… Expand
1998
1998
A novel cardiotonic agent SCH00013 acts as a Ca++ sensitizer with no chronotropic activity in mammalian cardiac muscle.
We investigated the inotropic effect of SCH00013 (4, 5-dihydro-6-[1-[2-hydroxy-2-(4-cyanophenyl)ethyl]-1,2,5, 6-tetrahydropyrido… Expand
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Highly Cited
1998
Highly Cited
1998
Modulation of cAMP-mediated vasorelaxation by endothelial nitric oxide and basal cGMP in vascular smooth muscle.
Recent in vitro evidence shows a role of endothelial nitric oxide (NO) in the modulation of isoproterenol-induced vasorelaxation… Expand
Review
1995
Review
1995
The effects of various drugs on the myocardial inotropic response.
  • M. Endoh
  • General pharmacology
  • 1995
    • Corpus ID: 25442414
1. The signal transduction process mediated by cyclic AMP that leads to the characteristic positive inotropic effect (PIE) in… Expand
1992
1992
Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, dopamine, dobutamine, denopamine and xamoterol in isolated human right atrium.
In patients with chronic heart failure cardiac beta-1 adrenoceptors are reduced, whereas beta-2 adrenoceptor changes vary… Expand
Highly Cited
1989
Highly Cited
1989
Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium.
Prenalterol (beta 1-agonist), denopamine (beta 1-agonist), and zinterol (beta 2-agonist) were partial agonists of adenylate… Expand
1988
1988
Details of Mode and Mechanism of Action of Denopamine, a New Orally Active Cardiotonic Agent with Affinity for β1‐Receptors
We investigated the detailed mode and mechanism of action of denopamine in canine right ventricular muscle. When administered in… Expand
Highly Cited
1986
Highly Cited
1986
Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor…
We used radioligand binding techniques and measurement of beta-agonist-mediated positive inotropic responses in isolated cardiac… Expand
Highly Cited
1986
Highly Cited
1986
β1‐ and β2‐Adrenergic‐Receptor Subpopulations in Nonfailing and Failing Human Ventricular Myocardium: Coupling of Both Receptor Subtypes to Muscle Contraction and Selective β1‐Receptor Down…
We used radioligand binding techniques and measurement of β-agonist-mediated positive inotropic responses in isolated cardiac… Expand
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