definitive hemopoiesis

Known as: definitive haematopoiesis, definitive haemopoiesis, definitive hematopoiesis 
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Notch signalling is a central regulator of differentiation in a variety of organisms and tissue types. Its activity is controlled… (More)
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Highly Cited
2007
Highly Cited
2007
Shifting sites of blood cell production during development is common across widely divergent phyla. In zebrafish, like other… (More)
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Highly Cited
2005
Highly Cited
2005
Homozygous loss of function of Runx1 (Runt-related transcription factor 1 gene) during murine development results in an embryonic… (More)
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Highly Cited
2005
Highly Cited
2005
We elucidate the cellular and molecular kinetics of the stepwise differentiation of human embryonic stem cells (hESCs) to… (More)
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Highly Cited
2003
Highly Cited
2003
The platelet glycoprotein IIb (alpha(IIb); CD41) constitutes the alpha subunit of a highly expressed platelet surface integrin… (More)
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Highly Cited
1999
Highly Cited
1999
In this study, we have mapped the onset of hematopoietic development in the mouse embryo using colony-forming progenitor assays… (More)
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Highly Cited
1998
Highly Cited
1998
In vertebrates, hematopoietic and vascular progenitors develop from ventral mesoderm. The first primitive wave of hematopoiesis… (More)
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Highly Cited
1997
Highly Cited
1997
Mouse embryos lacking the receptor tyrosine kinase, Flk1, die without mature endothelial and hematopoietic cells. To investigate… (More)
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Highly Cited
1997
Highly Cited
1997
The generation of blood cells, haematopoiesis, in the mouse embryo begins with the development of primitive nucleated erythroid… (More)
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Highly Cited
1996
Highly Cited
1996
The CBFA2 (AML1) gene encodes a DNA-binding subunit of the heterodimeric core-binding factor. The CBFA2 gene is disrupted by the… (More)
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