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deacetyldiltiazem

Known as: desacetyldiltiazem 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Diltiazem
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Effects of resveratrol on the pharmacokinetics of diltiazem and its major metabolite, desacetyldiltiazem, in rats.
The purpose of this study was to investigate the effects of resveratrol, an antioxidant, on the pharmacokinetics of diltiazem and… 
Highly Cited
2005
Highly Cited
2005
Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers
Highly Cited
2001
Highly Cited
2001
Pharmacokinetic interaction between single oral doses of ditiazem and sirolimus in healthy volunteers
The pharmacokinetic interaction between sirolimus, a macrolide immunosuppressant metabolized by CYP3A4, and the calcium channel… 
1995
1995
The Site of Absorption in the Small Intestine Determines Diltiazem Bioavailability in the Rabbit
AbstractPurpose. Since the ability of the small intestine to biotransform a drug may decrease in distal segments of the intestine… 
1992
1992
Pharmacokinetics and Pharmacodynamics of Intravenous Diltiazem in Patients With Atrial Fibrillation or Atrial Flutter
BackgroundDiltiazem, a calcium channel blocker, has been shown to be safe and effective in the treatment of patients in atrial… 
Highly Cited
1989
Highly Cited
1989
The pharmacokinetics and pharmacodynamics of diltiazem and its metabolites in healthy adults after a single oral dose
A potential complicating factor in the characterization of the pharmacokinetics and pharmacodynamics of diltiazem after an oral… 
Highly Cited
1985
Highly Cited
1985
Cardiovascular Effects of the Metabolites of Diltiazem in Dogs
The effects of diltiazem and some of its metabolites on the cardiovascular system were studied in anesthetized dogs and in blood… 
1985
1985
Diltiazem and desacetyldiltiazem analysis in human plasma using high-performance liquid chromatography: improved sensitivity without derivation.
Highly Cited
1984
Highly Cited
1984
Improved gas chromatographic determination of diltiazem and deacetyldiltiazem in human plasma.
This study describes an improved, simple, and specific gas chromatographic method for the determination of diltiazem (I) and… 
Highly Cited
1983
Highly Cited
1983
High-performance liquid chromatographic analysis of diltiazem and its metabolite in plasma.
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