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Diltiazem

Known as: 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-cis)-, Diltiazemum, (+)-cis-5-[2-(dimethylamino)Ethyl]-2,3-dihydro-3-hydroxy-2-(P-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester 
A benzothiazepine derivative with anti-hypertensive, antiarrhythmic properties. Diltiazem blocks voltage-sensitive calcium channels in the blood… 
National Institutes of Health

Related topics

Related topics

42 relations
24 HR Diltiazem Hydrochloride 120 MG Extended Release Oral Capsule [Cartia]24 HR Diltiazem Hydrochloride 120 MG Extended Release Oral Capsule [Dilt]24 HR Diltiazem Hydrochloride 120 MG Extended Release Oral Capsule [Diltia]24 HR Diltiazem Hydrochloride 240 MG Extended Release Oral Capsule

Broader (6)

Antihypertensive AgentsAzepinesBenzazepinesCalcium Channel Blockers

Narrower (15)

CardilCardizemDilacorDilacor XR

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1991
Highly Cited
1991
Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
Highly Cited
1990
Highly Cited
1990
Effects of diltiazem or lisinopril on massive proteinuria associated with diabetes mellitus.
Excerpt Recent studies in hypertensive, diabetic rats have shown that angiotensin-converting enzyme inhibitors reduce urinary… 
Highly Cited
1990
Highly Cited
1990
Alpha 1-adrenoceptor stimulation increases intracellular pH and Ca2+ in cardiomyocytes through Na+/H+ and Na+/Ca2+ exchange.
Highly Cited
1989
Highly Cited
1989
Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01.
Highly Cited
1987
Highly Cited
1987
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations.
Review
1987
Review
1987
Receptor pharmacology of calcium entry blocking agents.
Highly Cited
1985
Highly Cited
1985
Lack of evidence for voltage dependent calcium channels on platelets.
Highly Cited
1984
Highly Cited
1984
Potentiation of thermoregulatory and analgesic effects of morphine by calcium antagonists.
Highly Cited
1984
Highly Cited
1984
Uptake of calcium antagonistic drugs into muscles as related to their lipid solubilities.
Highly Cited
1982
Highly Cited
1982
Protective action of calcium channel antagonist agents against ventricular fibrillation in the isolated perfused rat heart.
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