dUTP pyrophosphatase

Known as: dUTPase, deoxyuridine triphosphate nucleotidylhydrolase, deoxyuridinetriphosphatase 
 

Topic mentions per year

Topic mentions per year

1975-2018
051019752018

Papers overview

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Highly Cited
2009
Highly Cited
2009
The innate immune response plays a key role as the primary host defense against invading pathogens including viruses. We have… (More)
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Highly Cited
2009
Highly Cited
2009
The thymine-uracil exchange constitutes one of the major chemical differences between DNA and RNA. Although these two bases form… (More)
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2003
2003
The amplification efficiencies of several polymerase chain reaction (PCR) enzymes were compared using real-time quantitative PCR… (More)
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2000
2000
Aberrant dUTP metabolism plays a significant role in the underlying molecular mechanisms of cell killing mediated by inhibitors… (More)
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2000
2000
dUTP pyrophosphatase (dUTPase) cleaves the alpha-beta phosphodiester of dUTP to form pyrophosphate and dUMP, preventing… (More)
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1999
1999
dUTPase is a ubiquitous and essential enzyme responsible for regulating cellular levels of dUTP. The dut gene exists as single… (More)
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1996
1996
We have determined the crystal structure of dUTP pyrophosphatase (dUTPase) from feline immunodeficiency virus (FIV) at 1.9 A… (More)
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Highly Cited
1993
Highly Cited
1993
dUTP pyrophosphatase (dUTPase; EC 3.6.1.23) catalyses the hydrolysis of dUTP to dUMP and PPi and thereby prevents the… (More)
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1992
1992
Two functional human dUTP pyrophosphatase (dUTPase; EC 3.6.1.23) cDNAs were isolated from a cDNA expression library by genetic… (More)
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1978
1978
Uracil is incorporated into newly synthesized DNA by mutants of Escherichia coli with reduced levels of dUTPase (dUTP… (More)
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