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cytostatin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2013
012319832013

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2 relations

Broader (2)

OrganophosphatesPyrones

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
cytostatin
Organophosphates
Pyrones

Papers overview

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2006
2006
Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.
The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is described in… (More)
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2004
2004
Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues.
The total synthesis of the natural product cytostatin is described which inhibits protein phosphatase 2A. Cytostatin has anti… (More)
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2004
2004
Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor.
Phosphorylation of synaptic (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) (AMPA) receptors (AMPARs) is an… (More)
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2003
2003
Synthesis and biological evaluation of cytostatin analogues.
Analogues of the serine/threonine phosphatase 2A inhibitor cytostatin were synthesized and evaluated as inhibitors of various… (More)
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2003
2003
Specific inhibitors of protein phosphatase 2A inhibit tumor metastasis through augmentation of natural killer cells.
Selective augmentation of natural killer (NK) cells can suppress tumor metastasis, but molecular targets for NK cell activation… (More)
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1999
1999
Cytostatin, an inhibitor of cell adhesion to extracellular matrix, selectively inhibits protein phosphatase 2A.
Cytostatin, which is isolated from a microbial cultured broth as a low molecular weight inhibitor of cell adhesion to… (More)
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1995
1995
Inhibitory effect of cytostatin on spontaneous lung metastases of B16-BL6 melanoma cells.
Tumorcells may interact with extracellular matrices (ECM) such as laminin, fibronectin and collagen type IV, at a variety of… (More)
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1994
1994
Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. II. Physico-chemical properties and structure determination.
The structure of cytostatin was determined to be 5,6-dihydro-5-methyl-6-(6-hydroxy,1,5-dimethyl-4-phosphonooxy-7,9, 11… (More)
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1994
1994
Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. I. Taxonomy, fermentation, isolation and biological activities.
Cytostatin has been identified as a novel inhibitor of cell adhesion to components of extracellular matrix (ECM) in cultured… (More)
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1992
1992
Effects of 17 beta-estradiol metabolites on cell cycle events in MCF-7 cells.
Different cell growth effects were observed in MCF-7 cells after six daily exposures to either 17 beta-estradiol (E2), 2… (More)
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