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cytostatin

National Institutes of Health

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OrganophosphatesPyrones

Papers overview

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2018
2018
The Cis-Δ 2 , 3-Double Bond of Phoslactomycins is Generated by a Post-PKS Tailoring Enzyme
The antifungal phoslactomycins (PLM A-F), produced by Streptomyes sp HK803, are structurally unusual in that three of their four… 
2006
2006
Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.
The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is described in… 
Highly Cited
2004
Highly Cited
2004
Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues.
The total synthesis of the natural product cytostatin is described which inhibits protein phosphatase 2A. Cytostatin has anti… 
2002
2002
Enantioselektive Totalsynthese und biologische Evaluierung des Protein-Phosphatase 2A Inhibitors Cytostatin und Analoga
1995
1995
Inhibitory effect of cytostatin on spontaneous lung metastases of B16-BL6 melanoma cells.
Tumorcells may interact with extracellular matrices (ECM) such as laminin, fibronectin and collagen type IV, at a variety of… 
1995
1995
Screening for apoptosis inducers in microbial products and induction of apoptosis by cytostatin.
We have employed the DNA-methylgreen binding assay as a primary screening method for identifying apoptosis inducers in microbial… 
1994
1994
Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. II. Physico-chemical properties and structure determination.
The structure of cytostatin was determined to be 5,6-dihydro-5-methyl-6-(6-hydroxy,1,5-dimethyl-4-phosphonooxy-7,9, 11… 
1992
1992
Effects of 17 beta-estradiol metabolites on cell cycle events in MCF-7 cells.
Different cell growth effects were observed in MCF-7 cells after six daily exposures to either 17 beta-estradiol (E2), 2… 
1983
1983
[Molecular mechanism of combined effect of amphotericin B and cyclophosphamide on a virus-induced neoplastic process].
Study of an experimental neoplastic process induced by virus type strains of Rous's sarcoma has shown that amphotericin B… 
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