cytidine deaminase activity

Known as: cytidine aminohydrolase activity, cytosine nucleoside deaminase activity 
Catalysis of the reaction: cytidine + H2O = uridine + NH3. [EC:3.5.4.5]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
051019692017

Papers overview

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2011
2011
APOBEC3G (A3G) is a deoxycytidine deaminase active on ssDNA substrates. In HIV infected cells A3G interacted with reverse… (More)
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2011
2011
The beneficial effects of DNA cytidine deamination by activation-induced deaminase (AID; antibody gene diversification) and… (More)
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Highly Cited
2005
Highly Cited
2005
The antiretroviral activity of the cellular enzyme APOBEC3G has been attributed to the excessive deamination of cytidine (C) to… (More)
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Highly Cited
2005
Highly Cited
2005
Human APOBEC3F and APOBEC3G are double-domained deaminases that can catalyze dC-->dU deamination in HIV-1 and MLV retroviral DNA… (More)
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Highly Cited
2005
Highly Cited
2005
The HIV-1 viral accessory protein Vif prevents the encapsidation of the antiviral cellular cytidine deaminases APOBEC3F and… (More)
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Highly Cited
2005
Highly Cited
2005
Antibodies, which are produced by B-lineage cells, consist of immunoglobulin heavy (IgH) and light (IgL) chains that have amino… (More)
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Highly Cited
1999
Highly Cited
1999
We have identified a novel gene referred to as activation-induced deaminase (AID) by subtraction of cDNAs derived from switch… (More)
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1999
1999
APOBEC-1, which mediates the editing of apolipoprotein (apo) B mRNA, is the only known member of the C (cytidine)-->U (uridine… (More)
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Highly Cited
1993
Highly Cited
1993
The messenger RNA for apolipoprotein B undergoes a discrete and specific C to U editing of nucleotide 6666. This generates a stop… (More)
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1987
1987
Cytidine deaminase is an enzyme of nucleic acid metabolism, the measurement of which has been proposed as a useful test for the… (More)
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