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cytidine deamination

The removal of amino group in the presence of water. [GOC:sm]
National Institutes of Health

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cytidine deaminase activity

Papers overview

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2018
2018
Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in…
Unrepaired uracils in DNA can lead to mutations and compromise genomic stability. Herpesviruses have hijacked host processes of… 
2018
2018
Human-APOBEC3G-dependent restriction of porcine endogenous retrovirus replication is mediated by cytidine deamination and inhibition of DNA strand transfer during reverse transcription
Although human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G, hA3G)-mediated deamination is the… 
2018
2018
AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates
In the course of both innate and adaptive immunity, cytidine deaminases within the activation induced cytidine deaminase (AID… 
2015
2015
The Frequency of Cytidine Editing of Viral DNA Is Differentially Influenced by Vpx and Nucleosides during HIV-1 or SIVMAC Infection of Dendritic Cells
Two cellular factors are currently known to modulate lentiviral infection specifically in myeloid cells: SAMHD1 and APOBEC3A (A3A… 
2011
2011
Mutation Vif-22H, which allows HIV-1 to use the APOBEC3G hypermutation to develop resistance, could appear more quickly in certain non-B variants.
Sir, HIV-1 Vif protein counteracts the lethal hypermutation produced by the cellular antiviral factor APOBEC3G (A3G) in HIV-1… 
2009
2009
Structure and real-time monitoring of the enzymatic reaction of APOBEC3G which is involved in anti-HIV activity.
Human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) is known to play a role in intrinsic cellular… 
2008
2008
NMR assignments and the identification of the secondary structure of the anti-retroviral cytidine deaminase.
APOBEC3G (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G) is known to have a role in intrinsic cellular… 
2007
2007
Activation-induced cytidine deaminase acts on double-strand breaks in vitro.
2006
2006
Involvement of Rad18 in somatic hypermutation
Somatic hypermutation of Ig genes is initiated by transcription-coupled cytidine deamination in Ig loci. Error-prone processing… 
Highly Cited
2003
Highly Cited
2003
Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination
Somatic hypermutation (SHM) and class switch recombination (CSR) are initiated by activation-induced cytidine deaminase–mediated… 
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