cyclophilin activity

Known as: cyclophilin 
OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity. [EC:5.2.1.8, ISBN:0198506732]

Topic mentions per year

Topic mentions per year

1984-2017
051019842017

Papers overview

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2012
2012
Posttranscriptional gene silencing is mediated by RNA-induced silencing complexes (RISCs) that contain AGO proteins and single… (More)
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2011
2011
BACKGROUND Cyclophilin inhibitors have shown activity against a variety of viruses, including HCV. NIM811, a novel, non… (More)
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Highly Cited
2008
Highly Cited
2008
UNLABELLED Debio-025 is an oral cyclophilin (Cyp) inhibitor with potent anti-hepatitis C virus activity in vitro. Its effect on… (More)
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Highly Cited
2005
Highly Cited
2005
The main regulators of leukocyte trafficking during inflammatory responses are chemokines. However, another class of recently… (More)
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1995
1995
Cyclosporins, in particular the nonimmunosuppressive derivative SDZ NIM 811, exhibit potent anti-human immunodeficiency virus… (More)
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1992
1992
During the purification of eosinophil chemotactic factors synthesized by the uterus in response to estrogen we isolated a protein… (More)
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1991
1991
Cyclosporin A bound to the presumed receptor protein cyclophilin was studied in aqueous solution at pH 6.0 by nuclear magnetic… (More)
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1990
1990
Cyclophilin is an abundant cytosolic protein that is expressed in most tissues and is found in all eukaryotic species examined… (More)
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1987
1987
Although several cytosolic proteins including calmodulin and cyclophilin have been shown to bind cyclosporine, the direct… (More)
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Highly Cited
1984
Highly Cited
1984
Cyclophilin, a specific cytosolic binding protein responsible for the concentration of the immunosuppressant cyclosporin A by… (More)
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