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cyclooxygenase pathway

The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase… 
National Institutes of Health

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Related topics

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prostaglandin biosynthetic process

Papers overview

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Highly Cited
2015
Highly Cited
2015
Leukotriene inhibitors attenuate rat lung injury induced by hydrogen peroxide.
It is known that reactive oxygen species cause lung injury in association with activation of arachidonate metabolism. Because… 
2002
2002
'Good' lipids for asthma
Asthma can originate via diverse causal and mechanistic pathways. A small bioactive lipid takes on this heterogeneity and offers… 
1995
1995
Prilocaine reduces injection pain caused by propofol
Propofol, which is commonly used for outpatient anaesthesia, may evoke pain during infusion. Forty‐eight patients (ASA I‐II… 
1992
1992
Down-regulation of cyclooxygenase product generation by human peritoneal macrophages.
Isolated human peritoneal macrophages under resting conditions synthesize and release significant quantities of the… 
1991
1991
Effects of bradykinin on intracellular calcium regulation in human ciliated airway epithelium.
The Ca(2+)-mobilizing action of bradykinin (BK) was investigated in ciliated human nasal epithelial (HNE) cells utilizing fura-2… 
Highly Cited
1987
Highly Cited
1987
Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig.
Guinea pigs were inoculated by nasal insufflation with parainfluenza 3 (P-3) or virus growth medium 4 days before performing in… 
Highly Cited
1983
Highly Cited
1983
The origin of chemiluminescence produced by neutrophils stimulated by opsonized zymosan.
The luminol-dependent chemiluminescence (CL) of neutrophils phagocytosing zymosan is inhibited by superoxide dismutase (SOD… 
1983
1983
Relative conversion of arachidonic acid through lipoxygenase and cyclooxygenase pathways by homogenates of diseased periodontal tissues.
The present study shows that 14C-arachidonic acid metabolism in gingiva of patients with periodontal disease is mainly via the… 
1982
1982
Phospholipase A2-induced rat mast cell secretion. Role of arachidonic acid metabolites.
Highly purified porcine phospholipase A2 induced noncytotoxic rat cell degranulation, as indicated by release of histamine… 
1980
1980
Aspirin: an unexpected side effect on prostacyclin synthesis in cultured vascular smooth muscle cells.
Monolayer cultures of rat aorta smooth muscle cells synthesized the anti-aggregatory substance prostacyclin via the… 
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