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cryptophycin

Known as: 10-((3-Chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-16-(1-(3-phenyloxiranyl)ethyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone 
The cryptophycins are a family of 16-membered macrolide antimitotic agents isolated from the cyanobacteria Nostoc sp. The mechanism of anticancer… 
National Institutes of Health

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Related topics

7 relations

Broader (5)

Antifungal AgentsAntineoplastic AgentsCryptophycinsDepsipeptides
Microtubule Processcryptophycin 1

Papers overview

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2016
2016
Microtubule targeting agents: mechanisms of action and classification Microtubules are dynamic tubular polymers of α- and β-tubulin which provide structural integrity, promote migration, transport of…
Microtubules are dynamic tubular polymers of αand β-tubulin which provide structural integrity, promote migration, transport of… 
2013
2013
Synthetic and Biocatalytic Methods for the Chemoenzymatic Production of Novel Cryptophycin Anticancer Agents.
..................................................................................................... xii Chapter 1: Introduction… 
2009
2009
[beta]2-Aminosäuren als Bausteine funktionalisierter Cryptophycin-Analoga
In preparation for a structure-activity relationship (SAR) study, 11 different analogues of the cytostatic compound cryptophycin… 
2005
2005
Synthesis of Cryptophycin Affinity Labels and Tubulin Labeling
Abstract : Cryptophycins are a potent, tumor-selective class of tubulin-binding antimitotic anti-cancer agents with excellent… 
2003
2003
Beiträge zu einer Totalsynthese von Cryptophycin
2000
2000
Apoptosis Induced by Cryptophycin in Renal Cancer Cell Line
Objective To study a new way of inducing renal cancer cell apoptosis.Methods The renal cancer cell apoptosis induced by… 
1997
1997
New cryptophine derivatives as antineoplasic agents.
THIS INVENTION REFERS TO NEW CRYPTOPHINE COMPOUNDS, WHICH CAN BE USEFUL FOR THE INTERRUPTION OF THE MICROTUBULIN SYSTEM, AS… 
1996
1996
The novel cryptophycin
(57) Abstract: The present invention provides novel cryptophycin having structure (I). Nostoc sp of the present invention may… 
1994
1994
The novel cryptophycin compounds
(57) Abstract: The present invention provides novel cryptophycin compounds having the structure (I). The present invention also… 
1994
1994
Cryptophycin A new microtubule depolymerizing agent which is active against drug-resistant cells