cryptophycin

Known as: 10-((3-Chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-16-(1-(3-phenyloxiranyl)ethyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone 
The cryptophycins are a family of 16-membered macrolide antimitotic agents isolated from the cyanobacteria Nostoc sp. The mechanism of anticancer… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
0246819942017

Papers overview

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2006
2006
LY355703 is a synthetic product structurally related to the cryptophycin family isolated from the blue-green algae, which exerts… (More)
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2000
2000
Exposure of murine leukemia L1210 cells to the antitumor antibiotic cryptophycin 52 (C52) led to cell-cycle arrest at the… (More)
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2000
2000
The antitumor activity of cryptophycin 52 (C52) and cryptophycin 55 (C55) in sequential and simultaneous combination treatment… (More)
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1999
1999
Purpose: Cryptophycin 52 (LY355703) is a new member of the cryptophycin family of antitumor agents that is currently undergoing… (More)
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1999
1999
The sponge-derived antimitotic tripeptide hemiasterlin was previously shown to inhibit tubulin polymerization. We have now… (More)
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1999
1999
Structure modification of the beta-alanine region (fragment C) of the potent antimitotic agent cryptophycin was investigated… (More)
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1997
1997
Cryptophycin 1 is a remarkably potent antiproliferative compound that shows excellent antitumor activity against mammary, colon… (More)
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1996
1996
Cryptophycin is a potent antitumor agent that depletes microtubules in intact cells, including cells with the multidrug… (More)
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1995
1995
The cryptophycins are newly discovered antimitotic agents isolated from the cyanobacterium Nostoc. Previous studies using… (More)
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1994
1994
Cryptophycin is a cytotoxic dioxadiazacyclohexadecenetetrone isolated from cyanobacteria of the genus Nostoc. Incubation of L1210… (More)
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