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cornified envelope

A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found… 
National Institutes of Health

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LCE1A geneLCE1F gene

Papers overview

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2016
2016
The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan divergence
BackgroundA common, 32kb deletion of LCE3B and LCE3C genes is strongly associated with psoriasis. We recently found that this… 
2003
2003
Characterization of Periphilin, a Widespread, Highly Insoluble Nuclear Protein and Potential Constituent of the Keratinocyte Cornified Envelope*
While keratinocytes go through the terminal differentiation and move toward the outer layers of epidermis, multiple proteins… 
1998
1998
Characterization of human involucrin promoter distal regulatory region transcriptional activator elements-a role for Sp1 and AP1 binding sites.
1998
1998
Temperature-sensitive regulation of epidermal morphogenesis and the expression of cornified envelope precursors by EGF and TGFα
Abstract Epidermis reconstructed on de-epidermized dermis was used to investigate the effects of growth factors and culture… 
1998
1998
The distal regulatory region of the human involucrin promoter is required for expression in epidermis.
1996
1996
Filaggrin linker segment peptide and cystatin alpha are parts of a complex of the cornified envelope of epidermis.
We showed that filaggrin linker segment peptide (FLSP) is a glutamine-rich substrate of epidermal transglutaminase (TGase… 
1994
1994
Binding of keratin intermediate filaments (K10) to the cornified envelope in mouse epidermis: implications for barrier function.
The cornified envelope, a structure unique to keratinocytes, is a hallmark of their terminal differentiation and plays an… 
Highly Cited
1987
Highly Cited
1987
Identification and subcellular distribution of cornified envelope precursor proteins in the transformed human keratinocyte line SV-K14.
SV-40 transformed human foreskin keratinocytes (line SV-K14) develop under conditions of serum starvation the competence to form… 
1987
1987
Characterization of monoclonal antibodies generated to the cornified envelope of human cultured keratinocytes.
The cornified envelope of keratinocytes is an insoluble structure formed beneath the plasma membrane at the base of the stratum… 
Highly Cited
1984
Highly Cited
1984
Keratolinin: the soluble substrate of epidermal transglutaminase from human and bovine tissue.
Substrates of human and bovine epidermal transglutaminase (glutaminyl-peptide gamma-glutamyltransferase, R-glutaminyl-peptide… 
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