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copolymer I (synthetic peptide)
Known as:
Cop 1
, copolymer I
, synthetic peptide copolymer I
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
(T,G)-A-L
synthetic peptide
Multiple Sclerosis
glatiramer acetate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Characterization of a Novel Non-Constitutive Photomorphogenic cop1 Allele1
M. Dieterle
,
C. Büche
,
E. Schäfer
,
T. Kretsch
Plant Physiology
2003
Corpus ID: 6721343
A specific light program consisting of multiple treatments with alternating red and far-red light pulses was used to isolate…
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Highly Cited
1999
Highly Cited
1999
Immunomodulation of experimental autoimmune encephalomyelitis by oral administration of copolymer 1.
D. Teitelbaum
,
R. Arnon
,
M. Sela
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 40463820
The activity of copolymer 1 (Cop 1, Copaxone, glatiramer acetate) in suppressing experimental autoimmune encephalomyelitis (EAE…
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Review
1997
Review
1997
Cop 1 as a candidate drug for multiple sclerosis.
D. Teitelbaum
,
R. Arnon
,
M. Sela
Journal of neural transmission. Supplementum
1997
Corpus ID: 8678329
Copolymer 1 (Cop 1), a synthetic copolymer of amino acids, is very effective in suppression of experimental autoimmune…
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1996
1996
Combinations of drugs
L. Kappos
Multiple Sclerosis
1996
Corpus ID: 9917094
As a result of recent therapeutic trials, recombinant Interferon beta (r/FNβ)-1b and-1a as well as Copolymer 1 (COP 1) and to…
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1990
1990
Cell-mediated immune response to copolymer I in multiple sclerosis measured by the macrophage procoagulant activity assay.
E. Grgacic
,
C. Bernard
International Immunology
1990
Corpus ID: 26986749
The macrophage/monocyte procoagulant activity (MPCA) assay, a sensitive and specific in vitro test for cell-mediated immunity…
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Highly Cited
1988
Highly Cited
1988
Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop 1.
D. Teitelbaum
,
R. Aharoni
,
R. Arnon
,
M. Sela
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 41836692
Cop 1 is a synthetic basic random copolymer of L-alanine, L-glutamic acid, L-lysine, and L-tyrosine in a residue molar ratio of 6…
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Highly Cited
1987
Highly Cited
1987
A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis.
M. Bornstein
,
A. Miller
,
+7 authors
V. Spada
New England Journal of Medicine
1987
Corpus ID: 33638687
Cop 1 is a random polymer (molecular weight, 14,000 to 23,000) simulating myelin basic protein. It is synthesized by polymerizing…
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1986
1986
Human cellular immune response to copolymer I and myelin basic protein
J. Burns
,
L. Krasner
,
F. Guerrero
Neurology
1986
Corpus ID: 8080801
Copolymer I (Cop I) is being tested as a treatment for MS because it protects animals against experimental allergic…
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1985
1985
Immunogenic potentials of copolymer I in normal human lymphocytes
C. Brosnan
,
M. Litwak
,
+4 authors
B. Bloom
Neurology
1985
Corpus ID: 11865771
Copolymer I (COP I), a nonencephalitogenic polypeptide analogous to myelin basic protein, is currently being tested for possible…
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Highly Cited
1982
Highly Cited
1982
Multiple sclerosis: Trial of a synthetic polypeptide
M. Bornstein
,
A. Miller
,
D. Teitelbaum
,
R. Arnon
,
M. Sela
Annals of Neurology
1982
Corpus ID: 34013107
A synthetic polypeptide, copolymer I (COP I), composed of alanine, glutamic acid, lysine, and tyrosine, has been demonstrated to…
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