copolymer I (synthetic peptide)

Known as: Cop 1, copolymer I, synthetic peptide copolymer I 
 
National Institutes of Health

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4 relations

Broader (2)

(T,G)-A-Lsynthetic peptide
Multiple Sclerosisglatiramer acetate

Papers overview

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2013
2013
Cop 1 for inhibiting weight loss, inducing weight regain or reducing macroscopic colonic damage in severe crohn's disease
 
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2003
2003
Characterization of a novel non-constitutive photomorphogenic cop1 allele.
A specific light program consisting of multiple treatments with alternating red and far-red light pulses was used to isolate… (More)
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1999
1999
Immunomodulation of experimental autoimmune encephalomyelitis by oral administration of copolymer 1.
The activity of copolymer 1 (Cop 1, Copaxone, glatiramer acetate) in suppressing experimental autoimmune encephalomyelitis (EAE… (More)
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Review
1997
Review
1997
Cop 1 as a candidate drug for multiple sclerosis.
Copolymer 1 (Cop 1), a synthetic copolymer of amino acids, is very effective in suppression of experimental autoimmune… (More)
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1996
1996
Combinations of drugs.
As a result of recent therapeutic trials, recombinant Interferon beta (rIFN beta)-Ib and -Ia as well as Copolymer I (COP I) and… (More)
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1988
1988
Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop 1.
Cop 1 is a synthetic basic random copolymer of L-alanine, L-glutamic acid, L-lysine, and L-tyrosine in a residue molar ratio of 6… (More)
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Highly Cited
1987
Highly Cited
1987
A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis.
Cop 1 is a random polymer (molecular weight, 14,000 to 23,000) simulating myelin basic protein. It is synthesized by polymerizing… (More)
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1986
1986
Human cellular immune response to copolymer I and myelin basic protein.
Copolymer I (Cop I) is being tested as a treatment for MS because it protects animals against experimental allergic… (More)
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1985
1985
Immunogenic potentials of copolymer I in normal human lymphocytes.
Copolymer I (COP I), a nonencephalitogenic polypeptide analogous to myelin basic protein, is currently being tested for possible… (More)
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1982
1982
Multiple sclerosis: trial of a synthetic polypeptide.
A synthetic polypeptide, copolymer I (COP I), composed of alanine, glutamic acid, lysine, and tyrosine, has been demonstrated to… (More)
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