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constitutive androstane receptor
Known as:
Constitutive Active Receptor
, CAR orphan nuclear receptor
, CAR nuclear receptor
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Nuclear receptor subfamily 1 group I member 3 (352 aa, ~40 kDa) is encoded by the human NR1I3 gene. This protein is involved in the regulation of…
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National Institutes of Health
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Related topics
Related topics
25 relations
Biologic Development
Cell Differentiation process
Cell Nucleus
Cell Proliferation
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Narrower (2)
NR1I3 protein, human
constitutive androstane receptor beta
Broader (1)
Receptors, Cytoplasmic and Nuclear
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor
R. Shizu
,
Sawako Shindo
,
Takemi Yoshida
,
S. Numazawa
PLoS ONE
2012
Corpus ID: 6957136
Constitutive androstane receptor (CAR) is a nuclear receptor that regulates the transcription of target genes, including CYP2B…
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2012
2012
Identification of Novel Activators of Constitutive Androstane Receptor from FDA-Approved Drugs by Integrated Computational and Biological Approaches
Caitlin Lynch
,
Yongmei Pan
,
+4 authors
Hongbing Wang
Pharmaceutical Research
2012
Corpus ID: 17950709
The constitutive androstane receptor (CAR, NR1I3) is a xenobiotic sensor governing the transcription of numerous hepatic genes…
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2011
2011
Constitutive Androstane Receptor Activation Decreases Plasma Apolipoprotein B–Containing Lipoproteins and Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice
A. Sberna
,
M. Assem
,
+11 authors
D. Masson
Arteriosclerosis, Thrombosis and Vascular Biology
2011
Corpus ID: 24894406
Objective—The goal of this study was to determine the impact of the nuclear receptor constitutive androstane receptor (CAR) on…
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2008
2008
Nuclear Receptor Coactivator 6 Mediates the Synergistic Activation of Human Cytochrome P-450 2C9 by the Constitutive Androstane Receptor and Hepatic Nuclear Factor-4α
S. Surapureddi
,
Ritu Rana
,
J. Reddy
,
J. Goldstein
Molecular Pharmacology
2008
Corpus ID: 13784786
Nuclear receptor coactivator 6 (NCOA6) also known as PRIP/RAP250/ASC-2 anchors a steady-state complex of cofactors and function…
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2008
2008
COP1D, an alternatively spliced constitutive photomorphogenic-1 (COP1) product, stabilizes UV stress-induced c-Jun through inhibition of full-length COP1
M. G. Savio
,
G. Rotondo
,
Stefano Maglie
,
G. Rossetti
,
J. Bender
,
R. Pardi
Oncogene
2008
Corpus ID: 20055138
COP1 is an evolutionarily conserved RING-finger ubiquitin ligase acting within a Cullin-RING ligase (CRL) complex that promotes…
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2005
2005
Structural Determinants of Constitutive Androstane Receptor Required for Its Glucocorticoid Receptor Interacting Protein-1-mediated Nuclear Accumulation*
Jun Xia
,
B. Kemper
Journal of Biological Chemistry
2005
Corpus ID: 41151395
Nuclear translocation of constitutive androstane receptor (CAR) is a primary mechanism for the induction of cytochrome P450 genes…
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Highly Cited
2003
Highly Cited
2003
Characterization of DNA Complexes Formed by the Nuclear Receptor Constitutive Androstane Receptor*
C. Frank
,
M. González
,
C. Oinonen
,
T. Dunlop
,
C. Carlberg
Journal of Biological Chemistry
2003
Corpus ID: 22365811
The nuclear receptor constitutive androstane receptor (CAR) acts as a xenobiotic sensor and regulates the expression of enzymes…
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2000
2000
p62 functions as a p38 MAP kinase regulator.
T. Sudo
,
M. Maruyama
,
H. Osada
Biochemical and Biophysical Research…
2000
Corpus ID: 36631046
By screening a HeLa cDNA library to isolate genes encoding p38-regulating proteins, we have isolated two independent clones which…
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1999
1999
A Novel Motif Mediates the Targeting of theArabidopsis COP1 Protein to Subnuclear Foci*
M. Stacey
,
A. V. von Arnim
Journal of Biological Chemistry
1999
Corpus ID: 9534595
The constitutive photomorphogenesis 1 (COP1) protein of Arabidopsis thaliana accumulates in discrete subnuclear foci. To better…
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1995
1995
Transcriptional Regulation of the Cholesteryl Ester Transfer Protein Gene by the Orphan Nuclear Hormone Receptor Apolipoprotein AI Regulatory Protein-1 (*)
F. Gaudet
,
G. Ginsburg
Journal of Biological Chemistry
1995
Corpus ID: 24846369
We have defined a 105-base pair tissue-restricted promoter for the cholesteryl ester transfer protein (CETP) gene that contains a…
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