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complestatin

Known as: chloropeptin II 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

ChlorophenolsCyclic Peptides

Narrower (1)

isocomplestatin

Papers overview

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2017
2017
Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster
We report the largest actinomycete genome to date, which encodes >30 secondary metabolites, including the kistamicin biosynthetic… 
2016
2016
Generation of New Complestatin Analogues by Heterologous Expression of the Complestatin Biosynthetic Gene Cluster from Streptomyces chartreusis AN1542
The heterologous expression of the biosynthetic gene cluster (BGC) of natural products enables the production of complex… 
2010
2010
Total synthesis of complestatin (chloropeptin II).
Complestatin was isolated in 1980 from the mycelium of Streptomyces lavendulae as inhibitor of alternative pathways to the… 
2005
2005
Isocomplestatin: total synthesis and stereochemical revision.
A Pd-mediated method for preparation of the strained macrocyclic moiety of complestatins is disclosed. Through stereoselective… 
Highly Cited
2001
Highly Cited
2001
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster
Streptomyces lavendulae produces complestatin, a cyclic peptide natural product that antagonizes pharmacologically relevant… 
2001
2001
Complestatin is a noncompetitive peptide antagonist of N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors: secure blockade of ischemic neuronal death.
Complestatin, a peptide derived from Streptomyces, was found to protect cultured cortical neurons from excitotoxicity induced by… 
Highly Cited
1999
Highly Cited
1999
Two syntheses of the 16- and 17-membered DEF ring systems of chloropeptin and complestatin.
[formula: see text] Two syntheses of a model system of the DEF ring system of complestatin and chloropeptin are described. The… 
1997
1997
Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. II. Structure elucidation of chloropeptin I.
The structure of chloropeptin I, a gp120-CD4 binding inhibitor having a potent anti-HIV activity, was elucidated by 1H and 13C… 
1997
1997
Enhancement of Plasminogen Binding to U937 Cells and Fibrin by Complestatin
Summary Plasminogen binds to endothelial and blood cells as well as to fibrin, where the zymogen is efficiently activated and… 
1997
1997
Enhancement of plasminogen binding and fibrinolysis by chloropeptin I.
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