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complestatin
Known as:
chloropeptin II
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Chlorophenols
Cyclic Peptides
Narrower (1)
isocomplestatin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.
Hiroyuki Shimamura
,
Steven P. Breazzano
,
Joie Garfunkle
,
F. S. Kimball
,
John D. Trzupek
,
D. Boger
Journal of the American Chemical Society
2010
Corpus ID: 5560104
Full details of the initial development and continued examination of a powerful intramolecular palladium(0)-mediated indole…
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2010
2010
Total synthesis of complestatin (chloropeptin II).
Zhihui Wang
,
M. Bois-choussy
,
Yanxing Jia
,
Jieping Zhu
Angewandte Chemie
2010
Corpus ID: 34286985
Complestatin was isolated in 1980 from the mycelium of Streptomyces lavendulae as inhibitor of alternative pathways to the…
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Highly Cited
2009
Highly Cited
2009
Total synthesis of chloropeptin II (complestatin) and chloropeptin I.
Joie Garfunkle
,
F. S. Kimball
,
+4 authors
D. Boger
Journal of the American Chemical Society
2009
Corpus ID: 207147870
The first total synthesis of chloropeptin II (1, complestatin) is disclosed. Key elements of the approach include the use of an…
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Highly Cited
2008
Highly Cited
2008
Synthesis of diastereomers of complestatin and chloropeptin I: substrate-dependent atropstereoselectivity of the intramolecular Suzuki-Miyaura reaction.
Yanxing Jia
,
M. Bois-choussy
,
Jieping Zhu
Angewandte Chemie
2008
Corpus ID: 46456312
Atropisomers as well as CC2 epimers of complestatin and chloropeptin I are readily synthesized through an intramol. SNAr reaction…
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2007
2007
Synthesis of DEFG ring of complestatin and chloropeptin I: highly atropdiastereoselective macrocyclization by intramolecular Suzuki-Miyaura reaction.
Yanxing Jia
,
M. Bois-choussy
,
Jieping Zhu
Organic Letters
2007
Corpus ID: 19418099
Palladium-catalyzed intramolecular Suzuki-Miyaura reaction of linear tripeptide (23) afforded the 16-membered DEFG ring of…
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Highly Cited
2001
Highly Cited
2001
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster
H. Chiu
,
B. Hubbard
,
+4 authors
C. Khosla
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 6275611
Streptomyces lavendulae produces complestatin, a cyclic peptide natural product that antagonizes pharmacologically relevant…
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Highly Cited
2001
Highly Cited
2001
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid…
S. B. Singh
,
H. Jayasuriya
,
+10 authors
D. Hazuda
Journal of Natural Products
2001
Corpus ID: 20003437
From the screening of a microbial extract library, isocomplestatin (1), a new axial-chiral isomer of complestatin (2) which is a…
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Highly Cited
1999
Highly Cited
1999
Two syntheses of the 16- and 17-membered DEF ring systems of chloropeptin and complestatin.
A. Elder
,
D. Rich
Organic Letters
1999
Corpus ID: 37812851
[formula: see text] Two syntheses of a model system of the DEF ring system of complestatin and chloropeptin are described. The…
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1997
1997
Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. II. Structure elucidation of chloropeptin I.
K. Matsuzaki
,
T. Ogino
,
T. Sunazuka
,
H. Tanaka
,
S. Ōmura
Journal of antibiotics (Tokyo. )
1997
Corpus ID: 22665068
The structure of chloropeptin I, a gp120-CD4 binding inhibitor having a potent anti-HIV activity, was elucidated by 1H and 13C…
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Highly Cited
1989
Highly Cited
1989
Complestatin, a potent anti-complement substance produced by Streptomyces lavendulae. I. Fermentation, isolation and biological characterization.
I. Kaneko
,
K. Kamoshida
,
S. Takahashi
Journal of antibiotics (Tokyo. )
1989
Corpus ID: 22062770
A new potent inhibitor of complement system, named complestatin, was isolated from the mycelium of Streptomyces lavendulae SANK…
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