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complement factor H, human

Known as: Human Factor H, H Factor 1, Factor H 
Complement factor H (1231 aa, ~139 kDa) is encoded by the human CFH gene. This protein is involved in the activation of the complement pathway.
National Institutes of Health

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2014
2014
Factor H binding protein (fHbp) is one of the main antigens of the 4‐component meningococcus B (4CMenB) multicomponent vaccine… Expand
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Highly Cited
2012
Highly Cited
2012
ABSTRACT Streptococcus suis serotype 2 is a Gram-positive bacterium that causes sepsis and meningitis in piglets and humans. The… Expand
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Highly Cited
2012
Highly Cited
2012
ABSTRACT Different capsular serotypes of Streptococcus pneumoniae vary markedly in their ability to cause invasive infection, but… Expand
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2011
2011
Bordetella pertussis causes whooping cough in humans, a highly contagious disease of the upper respiratory tract. An increase in… Expand
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2010
2010
ABSTRACT Meningococcal factor H-binding protein (fHbp) is a promising antigen that is part of two vaccines in clinical… Expand
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Highly Cited
2009
Highly Cited
2009
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy associated with mutations in complement proteins, most… Expand
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Highly Cited
2008
Highly Cited
2008
Complement forms a key arm of innate immune defenses against gonococcal infection. Sialylation of gonococcal lipo-oligosaccharide… Expand
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Highly Cited
2008
Highly Cited
2008
The long pentraxin PTX3 is a multifunctional soluble molecule involved in inflammation and innate immunity. As an acute phase… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Opsonization of bacteria by complement proteins is an important component of the immune response. The pathogenic… Expand
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Highly Cited
1998
Highly Cited
1998
Complement factor H (fH) regulates activation of the alternative pathway of C, reducing the amount of C3b deposited on sialic… Expand
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