complement factor H, human
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Factor H binding protein (fHbp) is one of the main antigens of the 4‐component meningococcus B (4CMenB) multicomponent vaccine… Expand SUMMARY Neisseria meningitidis is a Gram-negative microorganism that exists exclusively in humans and can cause devastating… Expand ABSTRACT Different capsular serotypes of Streptococcus pneumoniae vary markedly in their ability to cause invasive infection, but… Expand ABSTRACT Streptococcus suis serotype 2 is a Gram-positive bacterium that causes sepsis and meningitis in piglets and humans. The… Expand ABSTRACT Meningococcal factor H-binding protein (fHbp) is a promising antigen that is part of two vaccines in clinical… Expand Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy associated with mutations in complement proteins, most… Expand Complement forms a key arm of innate immune defenses against gonococcal infection. Sialylation of gonococcal lipo-oligosaccharide… Expand The long pentraxin PTX3 is a multifunctional soluble molecule involved in inflammation and innate immunity. As an acute phase… Expand ABSTRACT Opsonization of bacteria by complement proteins is an important component of the immune response. The pathogenic… Expand Complement factor H (fH) regulates activation of the alternative pathway of C, reducing the amount of C3b deposited on sialic… Expand