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cnicin

Known as: Centaurin, Cnicine, Cynisin 
A substance found in certain plants, including blessed thistle. It has been used in some cultures to treat certain medical problems. It may have anti… 
National Institutes of Health

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Related topics

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Broader (1)

Sesquiterpenes

Papers overview

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Highly Cited
2012
Highly Cited
2012
Bioactivity-guided isolation of antiproliferative compounds from Centaurea jacea L.
Highly Cited
2010
Highly Cited
2010
Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin α1
Phosphatidylinositol 3,4,5-triphosphate (PIP3) plays a key role in neuronal polarization and axon formation. PIP3-containing… 
Highly Cited
2007
Highly Cited
2007
Distinct profiles of expressed sequence tags during intestinal regeneration in the sea cucumber Holothuria glaberrima.
Repair and regeneration are key processes for tissue maintenance, and their disruption may lead to disease states. Little is… 
Highly Cited
2006
Highly Cited
2006
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.
Highly Cited
2005
Highly Cited
2005
Phytotoxic properties of cnicin, a sesquiterpene lactone fromcentaurea maculosa (spotted knapweed)
Water and solvent extracts from the aerial tissues ofCentaurea maculosa, spotted knapweed, inhibited the root growth of lettuce… 
Highly Cited
2004
Highly Cited
2004
Centaurin-α1 Is an in Vivo Phosphatidylinositol 3,4,5-Trisphosphate-dependent GTPase-activating Protein for ARF6 That Is Involved in Actin Cytoskeleton Organization*
The ADP-ribosylation factor (ARF) 6 small GTPase regulates vesicle trafficking and cytoskeletal actin reorganization. The GTPase… 
Highly Cited
2000
Highly Cited
2000
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.
The second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)] is generated by the action of phosphoinositide… 
Highly Cited
2000
Highly Cited
2000
Phosphoinositide-dependent Activation of the ADP-ribosylation Factor GTPase-activating Protein ASAP1
The ADP-ribosylation factor (Arf) family of GTP-binding proteins are regulators of membrane traffic and the actin cytoskeleton… 
Highly Cited
2000
Highly Cited
2000
The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton.
Arf family GTP-binding proteins are best characterized as regulators of membrane traffic, but recent studies indicate an… 
Review
2000
Review
2000
Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling.
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