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Diversity, ecological role and potential biotechnological applications of marine fungi associated to the seagrass Posidonia oceanica.
The results show that the mycoflora associated to P. oceanica is very rich and characterized by fungi able to produce ligninolytic enzymes and tannases useful to degrade and detoxify lignocellulose residues in presence of high salt concentrations. Expand
Chemistry and functional properties in prevention of neurodegenerative disorders of five Cistus species essential oils.
The results could promote the use of the essential oil of different Cistus species as food additives and for formulation of herbal infusion or nutraceutical products. Expand
Sesquiterpenoids in subtribe Centaureinae (Cass.) Dumort (tribe Cardueae, Asteraceae): distribution, (13)C NMR spectral data and biological properties.
This review summarizes reports on sesquiterpenoids from the Centaureinae subtribe of the Asteraceae family, as well as the (13)C NMR spectral data described in the literature, and reviews studies concerning the biological activities of these metabolites. Expand
Antibacterial and antioxidant activities in Sideritis italica (Miller) Greuter et Burdet essential oils.
The finding of antibacterial and antioxidant activities in the essential oils from Sideritis italica flowerheads and leaves validated the use of the plant for medical purposes. Expand
Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions.
The growth-inhibitory and proapoptotic effects of the eighteen sage essential oils were evaluated in three human melanoma cell lines, A375, M14, and A2058, and show that the main components were α-thujone, camphor, borneol, γ-muurolene and sclareol for all the samples, but the percentages varied depending on environmental factors such as altitude, water availability and pedo-climatic conditions. Expand
Antiproliferative activity of hexane extract from Tunisian Cistus libanotis, Cistus monspeliensis and Cistus villosus
The chemical composition of the hexane extracts from the three Cistus species can be useful in the chemosystematics of this complex genus and deserve further investigations to determine the compounds, or their combinations, which are the main responsible for the antiproliferative activity and its possible mechanism of action. Expand
Anti-HIV agents derived from the ent-kaurane diterpenoid linearol.
Five semisynthetic ent-kaurane derivatives of linearol showed significant activity against HIV replication in H9 lymphocyte cells with EC(50) values in the range <0.1-3.11 microg/mL, indicating potential for further development as potential anti-HIV agents. Expand
Semisynthetic derivatives of ent-kauranes and their antifeedant activity.
Although linearol did not influence the feeding behaviour of larvae of Spodoptera littoralis, some of its derivatives showed significant antifeedant activity. Expand
Abietane diterpenoids from the root of Salvia phlomoides
Abstract From the root of Salvia phlomoides three new abietane diterpenoids, demethylcryptojaponol, 14-deoxycoleon U and salviphlomone, have been isolated, besides the previously known diterpenesExpand
Metabolite profile and in vitro activities of Phagnalon saxatile (L.) Cass. relevant to treatment of Alzheimer’s disease
In vitro properties (inhibition of NO production and anticholinesterase) of Phagnalon saxatile (L.) Cass showed antioxidant activity that was measured by DPPH assay and β-carotene bleaching test and the compounds that most effectively inhibited lipopolysaccharide-induced NO production were caffeic acid and methylchlorogenic acid. Expand