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clorexolone
Known as:
6-chloro-2-cyclohexyl-2,3- dihydro-3-oxo-1H-isoindole-5-sulfonamide
, chlorexolone
A sulfonamide-based diuretic with thiazide-like activity. Cloreloxone has actions similar to that of thiazide diuretics.
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Isoindoles
Sulfonamides
decamethrin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1978
1978
Treatment of hypertension with single daily doses of acebutolol.
W. Leary
,
A. Asmal
,
P. Williams
,
B. Marwick
South African medical journal = Suid-Afrikaanse…
1978
Corpus ID: 12182079
The efficacy of single daily doses of acebutolol, alone or combined with chlorexolone, was investigated in a group of 20 ambulant…
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1976
1976
Lithium and the antidiuretic hormone.
S. Macneil
,
G. Jennings
,
P. Eastwood
,
C. Paschalis
,
F. Jenner
British Journal of Clinical Pharmacology
1976
Corpus ID: 44873350
The effect of lithium on the urine concentrating response to antidiuretic hormone (ADH) and the excretion of ADH has been studied…
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1973
1973
A controlled study of clopamide, clorexolone, and hydrochlorothiazide in diabetics.
B. Hicks
,
J. Ward
,
R. Jarrett
,
H. Keen
,
P. Wise
Metabolism: Clinical and Experimental
1973
Corpus ID: 11957944
Highly Cited
1971
Highly Cited
1971
Effect of diuretic therapy on glucose tolerance in hypertensive patients.
E. Kohner
,
C. Dollery
,
C. Lowy
,
B. Schumer
The Lancet
1971
Corpus ID: 37535916
1969
1969
Comparison of clorexolone, a new diuretic, with hydrochlorothiazide
R. Russell
,
P. V. Macaraeg
,
J. Schrogie
Clinical pharmacology and therapy
1969
Corpus ID: 41454073
The object of this study was to compare the metabolic and hypotensive effects of clorexolone, a new diuretic which is…
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1966
1966
Studies on the mechanism and characteristics of action of a new phthalimidine diuretic, clorexolone
W. Baba
,
A. Lant
,
G. Wilson
Clinical pharmacology and therapy
1966
Corpus ID: 36371545
A study aimed at investigating the mechanism and characteristics of action of a new phthalimidine diuretic, clorexolone, has been…
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1966
1966
The diuretic activity of clorexolone and some related phthalimides and 1‐oxoisoindolines
E. Cornish
,
G. Lee
,
W. R. Wragg
The Journal of pharmacy and pharmacology
1966
Corpus ID: 27092390
N‐Substituted 4‐chloro‐5‐sulphamoylphthalimides showed diuretic activity in the rat. Reduction of the carbonyl group in the…
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1966
1966
A Comparative Study with Clorexolone an Oral Hypotensive and Diuretic
J. Verbov
,
D. Tunstall‐Pedoe
,
T. Cooke
The British journal of clinical practice
1966
Corpus ID: 7176022
Diabetes is one of the complications of thiazide therapy and the following study was carried out to determine whether clorexolone…
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1965
1965
Metabolism of 5-Chloro-2-cyclohexyl-l-oxo-6-sulphamoyl Isoindoline, Clorexolone (M and B 8430)
K. Corbett
,
S. Edwards
,
G. Lee
,
T. Threlfall
Nature
1965
Corpus ID: 4251135
CLOREXOLONE (M and B 8430) is a powerful oral diuretic1 with pronounced antihypertensive properties even when administered in sub…
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1964
1964
Hypotensive Action of Hydrochlorothiazide and Clorexolone in the Conscious Normotensive Dog
D. Maxwell
,
J. Mclusky
Nature
1964
Corpus ID: 4265534
DIURETIC drugs of the benzothiadiazide type such as chlorothiazide and hydrochlorothiazide will cause a fall in both systolic and…
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