clonality (genetic analysis)

Known as: clonality 
 
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.
BACKGROUND Cancers arise from multiple acquired mutations, which presumably occur over many years. Early stages in cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15.
BACKGROUND Concomitant with the recent emergence of CTX-M-type extended-spectrum beta-lactamases (ESBLs), Escherichia coli has… (More)
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Highly Cited
2006
Highly Cited
2006
X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F…
The JAK2V617F mutation is present in most patients with polycythemia vera (PV) and in some patients with essential… (More)
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Highly Cited
2004
Highly Cited
2004
Genetic diversity, clonality and sexuality in Toxoplasma gondii.
The majority of Toxoplasma gondii strains from a variety of human and animal sources have been grouped into three highly clonal… (More)
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Review
2003
Review
2003
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2…
In a European BIOMED-2 collaborative study, multiplex PCR assays have successfully been developed and standardized for the… (More)
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Highly Cited
2002
Highly Cited
2002
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.
The deterioration in immune function with aging is thought to make a major contribution to the increased morbidity and mortality… (More)
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Highly Cited
2002
Highly Cited
2002
Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization
Adults maintain a reservoir of hematopoietic stem cells that can enter the circulation to reach organs in need of regeneration… (More)
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Highly Cited
1996
Highly Cited
1996
Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm
Mastocytosis Is characterized by accumulations of mast cells in various organs1. Most cases are indolent and confined to the skin… (More)
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Highly Cited
1994
Highly Cited
1994
Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy" [published erratum appears in J Exp Med 1994 Mar 1;179(3):1077]
To determine whether T cells, like B cells, can become clonally expanded in normal individuals as a function of age, we compared… (More)
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Highly Cited
1991
Highly Cited
1991
Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction.
The myeloproliferative syndromes are acquired disorders of hematopoiesis that provide insights into the transition from somatic… (More)
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