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ciprostene

Known as: 9beta-methyl-6alpha-carbaprostaglandin I2, 9beta-methylcarbacyclin, Pentanoic acid, 5-(hexahydro-5-hydroxy-6-(3-hydroxy-1-octenyl)-3a-methyl-2(1H)-pentalenylidene)-, (3aS-(2Z,3aalpha,5beta,6alpha(1E,3R*),6aalpha))- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Epoprostenol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Use of prostacyclin and its analogues in the treatment of cardiovascular disease.
Prostacyclin is found in all body tissues and body fluids, and is the major metabolite of arachidonic acid in the vasculature. It… 
1993
1993
Effects of prostacyclin analogues on human endothelial cell tissue factor expression.
Prostacyclin analogues have been reported to inhibit the expression of tissue factor procoagulant activity in human monocytes… 
1993
1993
Continuous Intravenous Dosing with Ciprostene Using a Portable Pump in Ambulatory Patients
Parenteral compounds present special drug delivery challenges. This open‐label study evaluated a portable infusion pump as a… 
1992
1992
Effects of ciprostene on restenosis rate during therapeutic transluminal coronary angioplasty.
Ciprostene, a chemically stable prostacyclin analog was studied for its effects on restenosis in patients with coronary artery… 
1992
1992
Prostacyclin analogues inhibit tissue factor expression in the human monocytic cell line THP-1 via a cyclic AMP-dependent mechanism.
Increased expression of tissue factor procoagulant by peripheral blood monocytes has been implicated in a number of thrombotic… 
1992
1992
Ciprostene and Indomethacin Partially Reverse the Mechanisms of Distal End Necrosis in the Rat Random Skin Flap
&NA; Survival of random skin flap distal end depends on hemodynamic, cellular, and coagulation mechanisms. This study was… 
Highly Cited
1991
Highly Cited
1991
U-61,431F, a stable prostacyclin analogue, inhibits the proliferation of bovine vascular smooth muscle cells with little antiproliferative effect on endothelial cells.
1986
1986
Tolerance and Pharmacology of Ciprostene, a Stable Epoprostenol (Prostacyclin) Analogue in Humans
Safety, tolerance, and pharmacology of 9‐beta‐methylcarbacyclin calcium (ciprostene calcium) was investigated in healthy male… 
1985
1985
The cardiovascular and platelet actions of 9β‐methyl carbacyclin (ciprostene), a chemically stable analogue of prostacyclin, in the dog and monkey
1 9β‐Methyl carbacyclin (9βMe; ciprostene) is a synthetic, chemically stable analogue of prostacyclin (PGI2; epoprostenol). The… 
1984
1984
Synthesis of 6a-carbaprostaglandin I3.
A synthesis of 6a-carbaprostaglandin I3 (2) was achieved in which the ω-chain was introduced by Wittig reaction of the optically… 
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