Skip to search formSkip to main contentSkip to account menu

cholylsarcosine

Known as: Glycine, N-methyl-N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)- 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Cholic AcidsSarcosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
[N-Methyl-11C]Cholylsarcosine, a Novel Bile Acid Tracer for PET/CT of Hepatic Excretory Function: Radiosynthesis and Proof-of-Concept Studies in Pigs
Excretion of conjugated bile acids into bile is an essential function of the liver, and impairment of canalicular bile acid… 
Highly Cited
2011
Highly Cited
2011
Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastro-intestinal fluids.
2010
2010
In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules.
Review
2009
Review
2009
Bile-acid-induced cell injury and protection.
Several studies have characterized the cellular and molecular mechanisms of hepatocyte injury caused by the retention of… 
2004
2004
Adjuvant Cholylsarcosine During Ursodeoxycholic Acid Treatment of Primary Biliary Cirrhosis
We postulated that coadministration ofcholylsarcosine with ursodeoxycholic acid might provideadditional benefit to primary… 
Highly Cited
2003
Highly Cited
2003
Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
Experiments were performed to test whether conjugated bile acid administration would decrease bacterial overgrowth, bacterial… 
Highly Cited
1999
Highly Cited
1999
Bile acid replacement therapy with cholylsarcosine for short-bowel syndrome.
BACKGROUND Fat malabsorption in the short-bowel syndrome (SBS) may in part be caused by decreased bile secretion. Cholylsarcosine… 
Highly Cited
1999
Highly Cited
1999
Conjugated bile acid replacement therapy for short-bowel syndrome.
Highly Cited
1993
Highly Cited
1993
Negative feedback regulation of the ileal bile acid transport system in rodents.
Highly Cited
1992
Highly Cited
1992
Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine.
The properties of cholylsarcosine (the synthetic N-acyl conjugate of cholic acid with sarcosine [N-methylglycine]) were examined… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License