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cholylsarcosine
Known as:
Glycine, N-methyl-N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)-
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Cholic Acids
Sarcosine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
[N-Methyl-11C]Cholylsarcosine, a Novel Bile Acid Tracer for PET/CT of Hepatic Excretory Function: Radiosynthesis and Proof-of-Concept Studies in Pigs
K. Frisch
,
S. Jakobsen
,
+5 authors
S. Keiding
The Journal of Nuclear Medicine
2012
Corpus ID: 1862575
Excretion of conjugated bile acids into bile is an essential function of the liver, and impairment of canalicular bile acid…
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Highly Cited
2011
Highly Cited
2011
Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastro-intestinal fluids.
J. Parmentier
,
M. Becker
,
U. Heintz
,
G. Fricker
International journal of pharmaceutics
2011
Corpus ID: 43381422
2010
2010
In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules.
J. Parmentier
,
F. Hartmann
,
G. Fricker
European journal of pharmaceutics and…
2010
Corpus ID: 46730622
Review
2009
Review
2009
Bile-acid-induced cell injury and protection.
Maria J Perez
,
O. Briz
World journal of gastroenterology
2009
Corpus ID: 23590650
Several studies have characterized the cellular and molecular mechanisms of hepatocyte injury caused by the retention of…
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2004
2004
Adjuvant Cholylsarcosine During Ursodeoxycholic Acid Treatment of Primary Biliary Cirrhosis
P. Ricci
,
A. Hofmann
,
L. Hagey
,
R. Jorgensen
,
E. Dickson
,
K. Lindor
Digestive Diseases and Sciences
2004
Corpus ID: 11739045
We postulated that coadministration ofcholylsarcosine with ursodeoxycholic acid might provideadditional benefit to primary…
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Highly Cited
2003
Highly Cited
2003
Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
V. Lorenzo-Zúñiga
,
R. Bartolí
,
+8 authors
M. Gassull
Hepatology
2003
Corpus ID: 25158303
Experiments were performed to test whether conjugated bile acid administration would decrease bacterial overgrowth, bacterial…
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Highly Cited
1999
Highly Cited
1999
Bile acid replacement therapy with cholylsarcosine for short-bowel syndrome.
S. Heydorn
,
P. Jeppesen
,
P. Mortensen
Scandinavian journal of gastroenterology
1999
Corpus ID: 19298349
BACKGROUND Fat malabsorption in the short-bowel syndrome (SBS) may in part be caused by decreased bile secretion. Cholylsarcosine…
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Highly Cited
1999
Highly Cited
1999
Conjugated bile acid replacement therapy for short-bowel syndrome.
C. Gruy-Kapral
,
K. H. Little
,
J. Fordtran
,
T. L. Meziere
,
L. Hagey
,
A. Hofmann
Gastroenterology
1999
Corpus ID: 24213177
Highly Cited
1993
Highly Cited
1993
Negative feedback regulation of the ileal bile acid transport system in rodents.
J. Lillienau
,
D. Crombie
,
J. Munoz
,
S. Longmire-Cook
,
L. Hagey
,
A. Hofmann
Gastroenterology
1993
Corpus ID: 42770747
Highly Cited
1992
Highly Cited
1992
Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine.
J. Lillienau
,
C. Schteingart
,
A. Hofmann
The Journal of clinical investigation
1992
Corpus ID: 22283912
The properties of cholylsarcosine (the synthetic N-acyl conjugate of cholic acid with sarcosine [N-methylglycine]) were examined…
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