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choline kinase activity

Known as: choline kinase (phosphorylating), ATP:choline phosphotransferase activity, choline-ethanolamine kinase activity 
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). [EC:2.7.1.32, RHEA:12840]
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

CDP-choline pathway
Choline Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse.
Highly Cited
2002
Highly Cited
2002
Regulation of choline kinase activity by Ras proteins involves Ral–GDS and PI3K
Ras proteins are molecular switches that control signaling pathways critical in the onset of a variety of human cancers. The… 
Highly Cited
1999
Highly Cited
1999
Increased Choline Kinase Activity in 1,2‐Dimethylhydrazine‐induced Rat Colon Cancer
Cancer cells acquire particular characteristics that benefit their proliferation. We previously reported that human colon cancers… 
1999
1999
Phosphorylation and Regulation of Choline Kinase fromSaccharomyces cerevisiae by Protein Kinase A*
The CKI1-encoded choline kinase (ATP:choline phosphotransferase, EC 2.7.1.32) from Saccharomyces cerevisiae was phosphorylated in… 
Highly Cited
1998
Highly Cited
1998
Expression, Purification, and Characterization of Choline Kinase, Product of the CKI Gene from Saccharomyces cerevisiae *
In the yeast Saccharomyces cerevisiae, choline kinase (ATP:choline phosphotransferase, EC2.7.1.32) is the product of the CKI gene… 
1996
1996
Characterization of Soybean Choline Kinase cDNAs and Their Expression in Yeast and Escherichia coli
An expressed sequence tag from Arabidopsis that displayed sequence homology to mammalian and yeast choline kinases was used to… 
Highly Cited
1995
Highly Cited
1995
Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines.
The effects of expression of the H-ras oncogene on phosphatidylcholine metabolism were examined in C3H10T1/2 and NIH3T3 cells… 
1990
1990
Repression of choline kinase by inositol and choline in Saccharomyces cerevisiae
The regulation of choline kinase (EC 2.7.1.32), the initial enzyme in the CDP-choline pathway, was examined in Saccharomyces… 
1986
1986
Several lines of evidence demonstrating that Plasmodium falciparum, a parasitic organism, has distinct enzymes for the phosphorylation of choline and ethanolamine
Highly Cited
1985
Highly Cited
1985
Regulation of choline kinase activity and phosphatidylcholine biosynthesis by mitogenic growth factors in 3T3 fibroblasts.
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