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choline kinase activity

Known as: choline kinase (phosphorylating), ATP:choline phosphotransferase activity, choline-ethanolamine kinase activity 
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). [EC:2.7.1.32, RHEA:12840]
National Institutes of Health

Papers overview

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2012
2012
Choline kinase catalyzes the phosphorylation of choline, the first step of phospholipid synthesis. Increased phosphorylation of… Expand
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2010
2010
Choline kinase in mammals is encoded by two genes, Chka and Chkb. Disruption of murine Chka leads to embryonic lethality, whereas… Expand
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Highly Cited
2002
Highly Cited
2002
Ras proteins are molecular switches that control signaling pathways critical in the onset of a variety of human cancers. The… Expand
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Highly Cited
1999
Highly Cited
1999
Cancer cells acquire particular characteristics that benefit their proliferation. We previously reported that human colon cancers… Expand
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1999
1999
The CKI1-encoded choline kinase (ATP:choline phosphotransferase, EC 2.7.1.32) from Saccharomyces cerevisiae was phosphorylated in… Expand
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1998
1998
In the yeast Saccharomyces cerevisiae, choline kinase (ATP:choline phosphotransferase, EC2.7.1.32) is the product of the CKI gene… Expand
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Highly Cited
1995
Highly Cited
1995
  • S. Ratnam, C. Kent
  • Archives of biochemistry and biophysics
  • 1995
  • Corpus ID: 24512309
The effects of expression of the H-ras oncogene on phosphatidylcholine metabolism were examined in C3H10T1/2 and NIH3T3 cells… Expand
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1990
1990
The regulation of choline kinase (EC 2.7.1.32), the initial enzyme in the CDP-choline pathway, was examined in Saccharomyces… Expand
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1986
1986
Choline kinase (EC 2.7.1.32) was investigated in plasmodium falciparum-infected erythrocytes. Disrupted infected erythrocytes had… Expand
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Highly Cited
1985
Highly Cited
1985
The regulation of choline kinase activity by fetal bovine serum and the regulation of phosphatidylcholine biosynthesis by choline… Expand
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