chemoprotection

The use of drugs to protect normal tissue from damage by cancer therapy agents.
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Consumption of a diet high in plant-based foods is associated with a decreased risk of epithelial cell cancers at several sites… (More)
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Review
2004
Review
2004
An important part of the cellular response to DNA damage is checkpoint activation — checkpoint kinases CHK1 and CHK2… (More)
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Highly Cited
2004
Highly Cited
2004
Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of phase 2… (More)
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Review
2001
Review
2001
One of the major mechanisms of protection against carcinogenesis, mutagenesis, and other forms of toxicity mediated by… (More)
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Highly Cited
2001
Highly Cited
2001
Induction of phase 2 enzymes, which neutralize reactive electrophiles and act as indirect antioxidants, appears to be an… (More)
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Review
2000
Review
2000
Induction of Phase 2 enzymes is an effective and sufficient strategy for achieving protection against the toxic and neoplastic… (More)
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Review
2000
Review
2000
One of the major mechanisms of protection against carcinogenesis, mutagenesis, and other forms of toxicity mediated by… (More)
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Review
1995
Review
1995
The glutathione S-transferases (GST) represent a major group of detoxification enzymes. All eukaryotic species possess multiple… (More)
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Review
1995
Review
1995
Mammalian cells have evolved elaborate mechanisms for protection against the toxic and neoplastic effects of electrophilic… (More)
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Highly Cited
1995
Highly Cited
1995
Quinone reductase [NAD(P)H:(quinone acceptor) oxidoreductase, EC 1.6.99.2], also called DT diaphorase, is a homodimeric FAD… (More)
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