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Detoxification of patulin and ochratoxin A, two abundant mycotoxins, by lactic acid bacteria.
Aim of the present study was to investigate the detoxification of two abundant mycotoxins, namely ochratoxin A (OTA) and patulin (PAT) which are frequently found in human foods, by lactic acidExpand
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Single cell gel electrophoresis assay: a new technique for human biomonitoring studies.
Human biomonitoring using the single cell gel electrophoresis (SCGE) or comet assay is a novel approach for the assessment of genetic damage in exposed populations. This assay enables the detectionExpand
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Genotoxic effects of heavy metals: Comparative investigation with plant bioassays
The potential use of micronucleus assays in plants for the detection of genotoxic effects of heavy‐metal ions was investigated. Three different plant systems were comparatively investigated inExpand
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Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.
Epidemiological studies give evidence that cruciferous vegetables (CF) protect humans against cancer, and also results from animal experiments show that they reduce chemically induced tumorExpand
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Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens.
The human hepatoma line (Hep G2) has retained the activities of various phase I and phase II enzymes which play a crucial role in the activation/detoxification of genotoxic procarcinogens and reflectExpand
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The use of the alkaline comet assay with lymphocytes in human biomonitoring studies.
We reviewed the data of 45 alkaline comet assay studies with lymphocytes published during the last three years with the objective of monitoring human exposure to genotoxic agents as a result ofExpand
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Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules.
SCOPE Coffee is among the most frequently consumed beverages. Its consumption is inversely associated to the incidence of diseases related to reactive oxygen species; the phenomenon may be due to itsExpand
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Genotoxic effects of ochratoxin A in human-derived hepatoma (HepG2) cells.
Ochratoxin A (OTA) is a widespread mycotoxin that occurs in many commodities from grains to coffee beans all over the world. Evidence is accumulating that OTA may cause cancer in humans. The compoundExpand
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DNA-protective effects of sumach (Rhus coriaria L.), a common spice: results of human and animal studies.
Sumach (Rhus coriaria L.) is widely used as a spice. The aim of this study was the investigation of its DNA-protective effects in humans and animals. Prevention of the formation of strand breaks andExpand
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Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC).
Two isothiocyanates (ITCs) commonly found in human diet, allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC), were tested for genotoxic effects in a battery of assays:Expand
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