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checkpoint kinase 2

Known as: Protein Kinase, Chk2, Kinase, PP1425 Protein, Kinase CHK2, Serine-Threonine-Protein 
Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Receptor-interacting protein kinase 1 (RIPK1) promotes cell survival—mice lacking RIPK1 die perinatally, exhibiting aberrant… Expand
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2011
2011
To the Editor,Germline mutations in high penetrance breast cancer sus-ceptibility genes, BRCA1 and BRCA2, account for… Expand
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Highly Cited
2008
Highly Cited
2008
Checkpoints are present in all phases of the cell cycle and are regarded as the gatekeepers maintaining the integrity of the… Expand
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2008
2008
NFBD1/MDC1, 53BP1, and BRCA1 are DNA damage checkpoint proteins with twin BRCT domains. In order to determine if they have… Expand
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2008
2008
Mitotic arrest deficiency protein 1 (Mad1) is associated with microtubule-unattached kinetochores in mitotic cells and is a… Expand
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2006
2006
Saccharomyces cerevisiae Rad53, the ortholog of mammalian Chk2, is an essential protein kinase in DNA damage and DNA replication… Expand
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2006
2006
The tumor suppressor gene Chk2 encodes a serine/threonine kinase that signals DNA damage to cell cycle checkpoints. In response… Expand
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2004
2004
On the basis of the results from our laboratory and others, we recently suggested that the ligand specificity of forkhead… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Human Polo-like kinase 3 (Plk3, previously termed Prk or Fnk) is involved in regulation of cell cycle progression… Expand
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Highly Cited
1999
Highly Cited
1999
The yeast serine/threonine kinase STE20 activates a signaling cascade that includes STE11 (mitogen-activated protein kinase… Expand
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