checkpoint kinase 2

Known as: Protein Kinase, Chk2, Kinase, PP1425 Protein, Kinase CHK2, Serine-Threonine-Protein 
Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
0102019852017

Papers overview

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2013
2013
Oroxylin A is a naturally occurring monoflavonoid isolated from the root of Scutellaria baicalensis Georgi, which has been used… (More)
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2013
2013
MYC levels are tightly regulated in cells, and deregulation is associated with many cancers. In this report, we describe the… (More)
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2011
2011
BACKGROUND The aim of this study was to screen molecular biomarkers for biodosimetry from DNA repair-related gene expression… (More)
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Highly Cited
2008
Highly Cited
2008
Checkpoints are present in all phases of the cell cycle and are regarded as the gatekeepers maintaining the integrity of the… (More)
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2006
2006
The tumor suppressor gene Chk2 encodes a serine/threonine kinase that signals DNA damage to cell cycle checkpoints. In response… (More)
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2006
2006
Clinical reports have suggested that low dietary folate increases risk for colorectal cancer. Animal studies for investigation of… (More)
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2006
2006
Saccharomyces cerevisiae Rad53, the ortholog of mammalian Chk2, is an essential protein kinase in DNA damage and DNA replication… (More)
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2005
2005
PURPOSE Activation of intracellular signaling cascades has been implicated in the growth control of benign meningiomas, but their… (More)
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2005
2005
We previously demonstrated that evodimine isolated from Evodia rutaecarpa (Goshuyu in Japan) induced apoptosis in human malignant… (More)
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2002
2002
Human Polo-like kinase 3 (Plk3, previously termed Prk or Fnk) is involved in regulation of cell cycle progression through the M… (More)
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