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checkpoint kinase 2

Known as: Protein Kinase, Chk2, Kinase, PP1425 Protein, Kinase CHK2, Serine-Threonine-Protein 
Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Receptor-interacting protein kinase 1 (RIPK1) promotes cell survival—mice lacking RIPK1 die perinatally, exhibiting aberrant… 
Highly Cited
2011
Highly Cited
2011
BackgroundInfection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell… 
Highly Cited
2008
Highly Cited
2008
Checkpoints are present in all phases of the cell cycle and are regarded as the gatekeepers maintaining the integrity of the… 
Highly Cited
2008
Highly Cited
2008
NFBD1/MDC1, 53BP1, and BRCA1 are DNA damage checkpoint proteins with twin BRCT domains. In order to determine if they have… 
2008
2008
Mitotic arrest deficiency protein 1 (Mad1) is associated with microtubule-unattached kinetochores in mitotic cells and is a… 
Highly Cited
2006
Highly Cited
2006
Saccharomyces cerevisiae Rad53, the ortholog of mammalian Chk2, is an essential protein kinase in DNA damage and DNA replication… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT Human Polo-like kinase 3 (Plk3, previously termed Prk or Fnk) is involved in regulation of cell cycle progression… 
Highly Cited
2002
Highly Cited
2002
The tumor suppressor function of p53 has been attributed to its ability to regulate apoptosis and the cell cycle. In mammals, DNA… 
Highly Cited
1999
Highly Cited
1999
The yeast serine/threonine kinase STE20 activates a signaling cascade that includes STE11 (mitogen-activated protein kinase…