ceramide biosynthetic process

Known as: ceramide formation, ceramide biosynthesis, ceramide anabolism 
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid. [GOC:ai]
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Obesity is associated with an enhanced inflammatory response that exacerbates insulin resistance and contributes to diabetes… (More)
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Review
2010
Review
2010
The suicidal death of erythrocytes or eryptosis is characterized by cell shrinkage, membrane blebbing and cell membrane… (More)
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Highly Cited
2008
Highly Cited
2008
Ceramide is among a number of potential lipotoxic molecules that are thought to modulate cellular energy metabolism. The heart is… (More)
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Highly Cited
2007
Highly Cited
2007
Insulin resistance occurs in 20%-25% of the human population, and the condition is a chief component of type 2 diabetes mellitus… (More)
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Highly Cited
2006
Highly Cited
2006
Accumulation of lipids in nonadipose tissues can lead to cell dysfunction and cell death, a phenomenon known as lipotoxicity… (More)
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Highly Cited
2004
Highly Cited
2004
Platelet-activating factor (PAF) induces pulmonary edema and has a key role in acute lung injury (ALI). Here we show that PAF… (More)
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Review
2003
Review
2003
The physiological role of ceramide formation in response to cell stimulation remains controversial. Here, we emphasize that… (More)
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Highly Cited
2001
Highly Cited
2001
Cytotoxic accumulation of long chain fatty acids has been proposed to play an important role in the pathogenesis of diabetes… (More)
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Highly Cited
1998
Highly Cited
1998
Like obese humans, Zucker diabetic fatty (ZDF) rats exhibit early beta cell compensation for insulin resistance (4-fold beta cell… (More)
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Highly Cited
1997
Highly Cited
1997
To identify cell death-induced genes, we employed a subtractive hybridization approach and isolated a cDNA encoding a mouse… (More)
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