centrosome cycle

The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of… (More)

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Topic mentions per year

1984-2018
024619842018

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2014
2014
As cells enter mitosis, the two centrosomes separate and grow dramatically, each forming a nascent spindle pole that nucleates a… (More)
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Highly Cited
2011
Highly Cited
2011
Primary microcephaly 1 is a neurodevelopmental disorder caused by mutations in the MCPH1 gene, whose product MCPH1 (also known as… (More)
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2010
2010
The two mitotic centrosomes direct spindle bipolarity to maintain euploidy. Centrosome amplification-the acquisition of > or =3… (More)
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2010
2010
Control of centrosome duplication is tightly linked with the progression of the cell cycle. Recent studies suggest that the… (More)
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2010
2010
Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong… (More)
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Highly Cited
2007
Highly Cited
2007
Tissue stem cells play a key role in tissue maintenance. Drosophila melanogaster central brain neuroblasts are excellent models… (More)
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2000
2000
To determine the molecular composition of the centrosome of a higher eukaryote, we carried out a systematic nano-electrospray… (More)
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Highly Cited
1998
Highly Cited
1998
Nek2, a mammalian protein kinase of unknown function, is closely related to the mitotic regulator NIMA of Aspergillus nidulans… (More)
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1997
1997
The absence of detailed in vitro studies leaves the molecular events involved in the centrosome cycle poorly characterized. Most… (More)
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Highly Cited
1992
Highly Cited
1992
Cyclin proteins form complexes with members of the p34cdc2 kinase family and they are essential components of the cell cycle… (More)
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