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centrosome separation
The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
centrosome cycle
Narrower (1)
mitotic centrosome separation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction
Balca R. Mardin
,
Cornelia Lange
,
+4 authors
E. Schiebel
Nature Cell Biology
2010
Corpus ID: 13903351
During interphase, centrosomes are held together by a proteinaceous linker that connects the proximal ends of the mother and…
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Highly Cited
2009
Highly Cited
2009
Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly
M. Tanenbaum
,
L. Macůrek
,
A. Janssen
,
Erica F. Geers
,
M. Álvarez-Fernández
,
R. Medema
Current Biology
2009
Corpus ID: 15875832
Highly Cited
2008
Highly Cited
2008
A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila
Jeroen Dobbelaere
,
Filipe Josué
,
S. Suijkerbuijk
,
B. Baum
,
N. Tapon
,
J. Raff
PLoS biology
2008
Corpus ID: 5892695
Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a…
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Highly Cited
2008
Highly Cited
2008
beta-Catenin is a Nek2 substrate involved in centrosome separation.
Shirin Bahmanyar
,
D. D. Kaplan
,
+7 authors
A. Barth
Genes & development
2008
Corpus ID: 13315106
beta-Catenin plays important roles in cell adhesion and gene transcription, and has been shown recently to be essential for the…
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Highly Cited
2008
Highly Cited
2008
Dynein, Lis1 and CLIP‐170 counteract Eg5‐dependent centrosome separation during bipolar spindle assembly
M. Tanenbaum
,
L. Macůrek
,
N. Galjart
,
R. Medema
The EMBO journal
2008
Corpus ID: 7925780
Bipolar spindle assembly critically depends on the microtubule plus‐end‐directed motor Eg5 that binds antiparallel microtubules…
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Highly Cited
2007
Highly Cited
2007
Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression
A. Lindqvist
,
Wouter van Zon
,
Christina Karlsson Rosenthal
,
R. Wolthuis
PLoS biology
2007
Corpus ID: 1762619
Activation of cyclin B1–cyclin-dependent kinase 1 (Cdk1), triggered by a positive feedback loop at the end of G2, is the key…
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Highly Cited
2004
Highly Cited
2004
Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase
A. Krämer
,
N. Mailand
,
+5 authors
J. Lukas
Nature Cell Biology
2004
Corpus ID: 22454669
Entry into mitosis occurs after activation of Cdk1, resulting in chromosome condensation in the nucleus and centrosome separation…
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Highly Cited
2002
Highly Cited
2002
CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells.
Zhihong Chen
,
Vahan B. Indjeian
,
Michael Mcmanus
,
Leyu Wang
,
B. Dynlacht
Developmental cell
2002
Corpus ID: 45367138
Highly Cited
1999
Highly Cited
1999
Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo
P. Gönczy
,
S. Pichler
,
M. Kirkham
,
A. Hyman
The Journal of cell biology
1999
Corpus ID: 7181446
We have investigated the role of cytoplasmic dynein in microtubule organizing center (MTOC) positioning using RNA-mediated…
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Highly Cited
1995
Highly Cited
1995
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
D. Glover
,
M. H. Leibowitz
,
D. McLean
,
H. Parry
Cell
1995
Corpus ID: 18085219
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