centrosome separation

The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate… (More)
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

centrosome cycle

Narrower (1)

mitotic centrosome separation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Breaking the ties that bind: New advances in centrosome biology
The centrosome, which consists of two centrioles and the surrounding pericentriolar material, is the primary microtubule… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2010
Review
2010
Mechanisms of centrosome separation and bipolar spindle assembly.
Accurate segregation of chromosomes during cell division is accomplished through the assembly of a bipolar microtubule-based… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
beta-Catenin is a Nek2 substrate involved in centrosome separation.
beta-Catenin plays important roles in cell adhesion and gene transcription, and has been shown recently to be essential for the… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression
Activation of cyclin B1-cyclin-dependent kinase 1 (Cdk1), triggered by a positive feedback loop at the end of G2, is the key… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Myosin II-Dependent Cortical Movement Is Required for Centrosome Separation and Positioning during Mitotic Spindle Assembly
The role of myosin II in mitosis is generally thought to be restricted to cytokinesis. We present surprising new evidence that… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase
Entry into mitosis occurs after activation of Cdk1, resulting in chromosome condensation in the nucleus and centrosome separation… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation
We show that human Cdc14A phosphatase interacts with interphase centrosomes, and that this interaction is independent of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo
We have investigated the role of cytoplasmic dynein in microtubule organizing center (MTOC) positioning using RNA-mediated… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Xklp2, a Novel Xenopus Centrosomal Kinesin-like Protein Required for Centrosome Separation during Mitosis
We describe a novel Xenopus plus end-directed kinesin-like protein (KLP), Xklp2, localized on centrosomes throughout the cell… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
We show that female sterile mutations of aurora (aur) are allelic to mutations in the lethal complementation group ck10. This… (More)
Is this relevant?